The human body hosts vast microbial communities, termed the microbiome. Less well
known is the fact that the human body also hosts vast numbers of different viruses …

Disease and accompanying inflammation are uncommon outcomes of viral infection in
humans. Clinical inflammation occurs if steady-state cell-intrinsic and leukocytic immunity to …

HPVs (human papillomaviruses) infect epithelial cells and their replication cycle is intimately
linked to epithelial differentiation. There are over 200 different HPV genotypes identified to …

Papillomaviruses have evolved over many millions of years to propagate themselves at
specific epithelial niches in a range of different host species. This has led to the great …

Human Papillomavirus (HPV) research has been dominated by the study of a subset of
Alpha papillomaviruses that together cause almost 5% of human cancers worldwide, with …

Persistent infection with human papillomavirus (HPV) initiates~ 5% of all human cancers,
and particularly cervical and oropharyngeal cancers. HPV vaccines prevent HPV infection …

Papillomaviruses induce benign and malignant epithelial tumors, and the viral E6
oncoprotein is essential for full transformation. E6 contributes to transformation by …

Abstract Purpose Primary immunodeficiency diseases (PIDs) comprise at least 176
hereditary disorders that are thought to be individually and collectively rare. The actual …

The American Academy of Allergy, Asthma & Immunology (AAAAI) and the American
College of Allergy, Asthma & Immunology (ACAAI) have jointly accepted responsibility for …

Papillomaviruses (PVs) are established agents of human and animal cancers. They infect
cutaneous and mucous epithelia. High Risk (HR) Human PVs (HPVs) are consistently …