Proper physiological function of the ovaries is very important for the entire female
reproductive system and overall health. Reactive oxygen species (ROS) are generated as …

In the efforts aimed at improving the quality of in-vitro-matured human oocytes, the dynamic
balance and roles of pro-/antioxidants merit further consideration. In-vitromaturation (IVM) is …

The time-lapse system is a non-invasive method that enables a continuous evaluation
through embryo development. Here, we examined the association between the …

Mammalian oocytes represent impaired quality after undergoing a process of postovulatory
aging, which can be alleviated through various effective ways such as reagent treatment …

Although it is well established that maturation conditions have a clear influence on oocyte
developmental competence, it is not known whether this could be due to downstream effects …

Recent studies have shown that l-proline (proline) is an antioxidant to protect cells from
oxidative stress in vivo and in vitro. Glutathione (GSH) is a major cellular redox regulator …

Small RNA represent several unique noncoding RNA classes that have important function in
the development of germ cells and early embryonic development. Deep sequencing was …

Cryopreservation may lead bovine oocytes to undergo morphological changes and
functional damage due to the high-lipid content in the cytoplasm and the formation of …

The age at which women have their first child is increasing. This change represents a major
health problem to society because advanced maternal age is related with a decay in fertility …

Decrease in quality of postovulatory aged oocytes occurs due to oxidative stress and leads
to low fertilization and development competence. It is one of the main causes that exerting …