Ubiquitin ligases: guardians of mammalian development
DA Cruz Walma, Z Chen, AN Bullock… - … Reviews Molecular Cell …, 2022 - nature.com
Mammalian development demands precision. Millions of molecules must be properly
located in temporal order, and their function regulated, to orchestrate important steps in cell …
located in temporal order, and their function regulated, to orchestrate important steps in cell …
The functional analysis of Cullin 7 E3 ubiquitin ligases in cancer
L Shi, D Du, Y Peng, J Liu, J Long - Oncogenesis, 2020 - nature.com
Cullin (CUL) proteins have critical roles in development and cancer, however few studies on
CUL7 have been reported due to its characteristic molecular structure. CUL7 forms a …
CUL7 have been reported due to its characteristic molecular structure. CUL7 forms a …
Aberrant NSG1 expression promotes esophageal squamous cell carcinoma cell EMT by the activation of ERK signaling pathway
X Lin, M Tu, Y Zhang, W Zhuang, L Cai, L Zhang… - Digestive Diseases and …, 2023 - Springer
Background Neuron-specific gene family member 1 (NSG1) is a 21 kDa endosomal protein
that is specifically expressed in neurons. Aims This study was to explore the expression of …
that is specifically expressed in neurons. Aims This study was to explore the expression of …
Tet methylcytosine dioxygenase 2 (TET2) deficiency elicits EGFR-TKI (tyrosine kinase inhibitors) resistance in non-small cell lung cancer
J Zhang, K Zhao, W Zhou, R Kang, S Wei… - … and Targeted Therapy, 2024 - nature.com
Despite epidermal growth factor receptor (EGFR) tyrosine kinase inhibitors (TKI) have
shown remarkable efficacy in patients with EGFR-mutant non-small cell lung cancer …
shown remarkable efficacy in patients with EGFR-mutant non-small cell lung cancer …
Identification of key regulators in prostate cancer from gene expression datasets of patients
Identification of key regulators and regulatory pathways is an important step in the discovery
of genes involved in cancer. Here, we propose a method to identify key regulators in …
of genes involved in cancer. Here, we propose a method to identify key regulators in …
A Comprehensive Review and Androgen Deprivation Therapy and Its Impact on Alzheimer's Disease Risk in Older Men with Prostate Cancer
Prostate cancer (PCa) is one of the most prevalent malignancies affecting males worldwide.
Despite reductions in mortality rates due to advances in early identification and treatment …
Despite reductions in mortality rates due to advances in early identification and treatment …