[HTML][HTML] Strategies for prevention and management of ocular events occurring with mirvetuximab soravtansine

A Hendershot, M Slabaugh, KM Riaz, KN Moore… - Gynecologic Oncology …, 2023 - Elsevier
Mirvetuximab soravtansine (MIRV) is a first-in-class antibody-drug conjugate (ADC)
targeting folate receptor alpha (FRα) and is indicated for the treatment of adult patients with …

Quantitative Raman chemical imaging of intracellular drug-membrane aggregates and small molecule drug precipitates in cytoplasmic organelles

V LaLone, D Smith, J Diaz-Espinosa… - Advanced Drug Delivery …, 2023 - Elsevier
Raman confocal microscopes have been used to visualize the distribution of small molecule
drugs within different subcellular compartments. This visualization allows the discovery …

Ocular effects of Rho kinase (ROCK) inhibition: a systematic review

JB Lin, JM Harris, G Baldwin, D Goss, MA Margeta - Eye, 2024 - nature.com
Topical therapies targeting Rho-associated protein kinase (ROCK) signalling, including
netarsudil (Rhopressa®) and ripasudil (Glanatec®), have become widely adopted as part of …

Impact of Nontreatment Duration and Keratopathy on Major Adverse Cardiovascular Events in Fabry Disease: A Nationwide Cohort Study

A Yang, S Kim, YJ Choi - Journal of Clinical Medicine, 2024 - mdpi.com
Fabry disease (FD) is a rare inherited X-linked lysosomal storage disorder that results in the
progressive accumulation of glycosphingolipids in multiple organs. Early FD-specific …

[HTML][HTML] Unambiguous Interpretation of the Pathogenicity of the GLA c. 547+ 3A> G Variant Causing Fabry Disease

M Urtis, C Cavaliere, V Vilardo, C Paganini… - Genes, 2024 - mdpi.com
Objectives: This study aims to demonstrate the role of case-level American College of
Medical Genetics (ACMG) criteria, such as familial segregation and pathology data, in …

[HTML][HTML] Crystalline keratopathy following long-term netarsudil therapy

OW Cummings, JM Meléndez-Montañez… - American Journal of …, 2024 - Elsevier
Purpose This case report highlights a possible association between netarsudil use and
crystalline keratopathy. Observations Presented here is the case of a 72-year-old woman …

[HTML][HTML] DICED-anti-depressant drug-induced corneal endothelial deposits

J Christy, M Nair, S Tagare - Indian Journal of Psychiatry, 2023 - journals.lww.com
Tricyclic Antidepressants (TCA) and Selective Serotonin Reuptake Inhibitors (SSRI) are a
common class of drugs used in the treatment of depressive disorders. They are also known …

[HTML][HTML] Ocular Manifestations of Fabry Disease: Report from a Tertiary Eye Care Center in Türkiye

İ Korkmaz, SK Uçar, H Onay, EY Sözmen… - Turk J …, 2024 - oftalmoloji.org
Objectives To report ocular manifestations in patients with Fabry disease (FD) from a tertiary
eye care center in Türkiye. Materials and Methods: This prospective, cross-sectional study …

[PDF][PDF] Feasibility of a Minimally Invasive Descemet's Stripping Only Procedure using Laser (Laser-DSO) for Treating Corneal Endothelial Disease using an Ex Vivo …

L Kopecny - 2023 - unsworks.unsw.edu.au
Fuch's Endothelial Corneal Dystrophy (FECD) is the leading cause of visually significant
corneal endothelial (CE) failure in Western countries3, estimated to affect 4% of the United …

Dangers in the use of systemic and local drugs expressed in eye disorders–a literature review

P Ziemba, A Janocha, A Jerzak, K Jakubowska - Quality in Sport, 2024 - apcz.umk.pl
Materials and methods The methodology for conducting literature search involved utilizing
medical subject headings terms to explore PubMed. Search terms included:“drug-induced …