The study of proteins circulating in blood offers tremendous opportunities to diagnose,
stratify, or possibly prevent diseases. With recent technological advances and the urgent …

Fibrin is a major component of thrombi formed on the surface of atherosclerotic plaques.
Fibrin accumulation as a consequence of local blood coagulation activation takes place …

Obesity is mostly associated with adverse health consequences, but may also elicit
favorable effects under chronic conditions. This “obesity paradox” is under debate for …

Venous thromboembolism is associated with formation of denser fibrin clots resistant to lysis.
We investigated whether prothrombotic plasma clot properties are associated with the …

Patients with cirrhosis frequently acquire profound hemostatic alterations, which may affect
thrombus quality and composition—factors that determine the susceptibility to embolization …

The immune complement and the coagulation systems are blood-based proteolytic
cascades that are activated by pathway-specific triggers, based on protein–protein …

Background: Elevated plasma lactate levels correlate with high mortality rate in acute
pulmonary embolism (PE) patients. We hypothesized that elevated lactate levels correlate …

Introduction Several methods for measuring fibrinolytic capacity in plasma have been
developed yielding frequently inconsistent results. We investigated which factors determine …

Proteomics, the simultaneous study of all proteins in a given cell, tissue or organism, is an
innovative approach used to identify novel markers for diagnosis, prognosis and the …

Background Residual pulmonary vascular obstruction (RPVO) is common following
pulmonary embolism (PE) but its association with fibrin clot properties is poorly understood …