Insect cecropins, antimicrobial peptides with potential therapeutic applications

D Brady, A Grapputo, O Romoli, F Sandrelli - International journal of …, 2019 - mdpi.com
The alarming escalation of infectious diseases resistant to conventional antibiotics requires
urgent global actions, including the development of new therapeutics. Antimicrobial peptides …

Peptides with dual antimicrobial–anticancer activity: Strategies to overcome peptide limitations and rational design of anticancer peptides

Y Liscano, J Oñate-Garzón, JP Delgado - Molecules, 2020 - mdpi.com
Peptides are naturally produced by all organisms and exhibit a wide range of physiological,
immunomodulatory, and wound healing functions. Furthermore, they can provide with …

[HTML][HTML] Insects: an underrepresented resource for the discovery of biologically active natural products

L Seabrooks, L Hu - Acta Pharmaceutica Sinica B, 2017 - Elsevier
Nature has been the source of life-changing and-saving medications for centuries. Aspirin,
penicillin and morphine are prime examples of Nature׳ s gifts to medicine. These discoveries …

[HTML][HTML] Beetles as model organisms in physiological, biomedical and environmental studies–a review

Z Adamski, SA Bufo, S Chowański, P Falabella… - Frontiers in …, 2019 - frontiersin.org
Model organisms are often used in biological, medical and environmental research. Among
insects, Drosophila melanogaster, Galleria mellonella, Apis mellifera, Bombyx mori …

Purification and characterization of foxtail millet-derived peptides with antioxidant and antimicrobial activities

I Amadou, GW Le, T Amza, J Sun, YH Shi - Food Research International, 2013 - Elsevier
In this study, we describe the purification by RP-HPLC and amino acid sequencing by LC-
MS of peptides derived from foxtail millet (Setaria italica) meal fermented by Lactobacillus …

[HTML][HTML] Recent advances in developing insect natural products as potential modern day medicines

N Ratcliffe, P Azambuja, CB Mello - Evidence-based complementary …, 2014 - hindawi.com
Except for honey as food, and silk for clothing and pollination of plants, people give little
thought to the benefits of insects in their lives. This overview briefly describes significant …

Snake venoms: attractive antimicrobial proteinaceous compounds for therapeutic purposes

NG de Oliveira Junior, MH e Silva Cardoso… - Cellular and molecular …, 2013 - Springer
Gram-positive and-negative bacteria are dangerous pathogens that may cause human
infection diseases, especially due to the increasingly high prevalence of antibiotic …

Interaction between Metarhizium anisopliae and Its Host, the Subterranean Termite Coptotermes curvignathus during the Infection Process

SA Syazwan, SY Lee, AS Sajap, WH Lau, D Omar… - Biology, 2021 - mdpi.com
Simple Summary The use of Metarhizium anisopliae as a biological control of insect pests
has been experimented in the laboratory as well as in field trials. This includes against the …

A Defensin from the Model Beetle Tribolium castaneum Acts Synergistically with Telavancin and Daptomycin against Multidrug Resistant Staphylococcus aureus

R Rajamuthiah, E Jayamani, AL Conery, BB Fuchs… - PLoS …, 2015 - journals.plos.org
The red flour beetle Tribolium castaneum is a common insect pest and has been established
as a model beetle to study insect development and immunity. This study demonstrates that …

Bacterial but not fungal challenge up‐regulates the transcription of Coleoptericin genes in Tenebrio molitor

HA Jang, KB Park, BB Kim… - Entomological …, 2020 - Wiley Online Library
Antimicrobial peptides (AMPs) are effector candidates that elicit humoral immunity in
invertebrates. AMPs facilitate bacterial clearance by either physically disrupting the …