To investigate the clinical impact of multiple courses of irradiation on pediatric patients with
progressive diffuse intrinsic pontine glioma (DIPG), we conducted a retrospective case …

Targeted therapies, including small molecule inhibitors directed against aberrant kinase
signaling and chromatin regulators, are emerging treatment options for high-grade gliomas …

Glioblastoma (GBM) is the most malignant and aggressive primary brain tumor and is highly
resistant to current therapeutic strategies. Previous studies have demonstrated that reactive …

Glioblastoma is a primary brain tumor associated with a poor prognosis due to its high
chemoresistance capacity. Cancer stem cells (CSCs) are one of the mechanisms of …

Purpose: Parallel signaling reduces the effects of receptor tyrosine kinase (RTK)–targeted
therapies in glioma. We hypothesized that inhibition of protein N-linked glycosylation, an …

Glioblastoma (GBM) is a deadly brain cancer, and all attempts to control it have failed so far.
However, the future looks bright, as we now know the molecular landscape of GBM through …

Background Galectin-1, a radioresistance marker, was found in our previous study to be a
prognostic factor for cervical cancer. The aim of current study is to determine the prognostic …

Background Precision medicine trials targeting the epidermal growth factor receptor (EGFR)
in glioblastoma patients require selection for EGFR-amplified tumors. However, there is …

Purpose: Glioblastoma multiforme (GBM) is an aggressive primary brain tumor that is radio-
resistant and recurs despite aggressive surgery, chemo, and radiotherapy. Autotaxin (ATX) …

Gliomas are the most common primary central nervous system tumors; despite recent
advances in diagnosis and treatment, glioma patients generally have a poor prognosis …