Background Idiopathic pulmonary fibrosis (IPF) is a chronic, progressive disease
characterized by the aberrant accumulation of fibrotic tissue in the lungs parenchyma …

Introduction: Many forms of interstitial lung disease (ILD) can progress to extensive fibrosis
and respiratory failure. Idiopathic pulmonary fibrosis (IPF), which generally has a poor …

Bronchiectasis is a clinical and radiological diagnosis associated with cough, sputum
production and recurrent respiratory infections. The clinical presentation inevitably overlaps …

Despite the development of pharmacological therapies that are effective in slowing the
progression of idiopathic pulmonary fibrosis (IPF), it remains a debilitating and lethal …

Cellular senescence, the irreversible loss of replicative capacity in somatic cells, plays a
causal role in the development of age-related pathology and in a number of age-related …

Hypoxia-induced pulmonary hypertension (PH) is one of the most common and deadliest
forms of PH. Fibroblast growth factor receptors 1 and 2 (FGFR1/2) are elevated in patients …

Background The clinical impact of interstitial lung abnormalities (ILAs) on poor prognosis
has been reported in many studies, but risk stratification in ILA will contribute to clinical …

Background Treatment and preventative advances for chronic obstructive pulmonary
disease (COPD) have been slow due, in part, to limited subphenotypes. We tested if …

Introduction Smoking-associated interstitial lung disease manifests as several
heterogeneous disorders involving the airways, pleura, and lung parenchyma with various …

Abstract The 2015 European Guidelines on Pulmonary Hypertension did not only cover
pulmonary arterial hypertension (PAH) but also some aspects of pulmonary hypertension …