The exact connection between Alzheimer's disease (AD) and type 2 diabetes is still in
debate. However, poorly controlled blood sugar may increase the risk of developing …

Alzheimer's disease (AD) is the most common cause of dementia and a great
socioeconomic burden in the aging society. Compelling evidence demonstrates that …

As a chronic metabolic disease, diabetes mellitus (DM) is broadly characterized by elevated
levels of blood glucose. Novel epidemiological studies demonstrate that some diabetic …

Alzheimer's disease (AD) is the most prevalent form of dementia, particularly in old age
subjects. Hyperinsulinemia and insulin resistance, which are known as pathophysiological …

Alzheimer's (or Alzheimer) disease (AD) is the most prevalent subset of dementia, affecting
elderly populations worldwide. The cumulative costs of the AD care are rapidly accelerating …

Blood glucose homeostasis is well maintained by coordinated control of various hormones
including insulin and glucagon as well as cytokines under normal conditions. However …

Insulin‐degrading enzyme (IDE) function goes far beyond its known proteolytic role as a
regulator of insulin levels. IDE has a wide substrate promiscuity, degrading several proteins …

Alzheimer's disease (AD) is well-known as a severe neurodegeneration disease involving
complicated etiologies, and cholinesterase inhibition remain the prevailing mode of clinical …

A growing number of clinical and epidemiological studies support the hypothesis of a tight
correlation between type 2 diabetes mellitus (T2DM) and the development risk of …

Recent studies continue to find evidence linking Type 2 diabetes (T2D) with Alzheimer's
disease (AD), the most common cause of dementia, a general term for memory loss and …