Lipids are crucial components of cellular function owing to their role in membrane formation,
intercellular signaling, energy storage, and homeostasis maintenance. In the brain, lipid …

Increasing evidence supports the notion that neuroinflammation plays a critical role in the
etiology of major depressive disorder (MDD), at least in a subset of patients. By virtue of their …

In the past decades, reductionism has dominated both research directions and funding
policies in clinical psychology and psychiatry. The intense search for the biological basis of …

Background Dyslipidaemia is one of the most prevalent metabolic disturbances observed in
schizophrenia patients and has been largely attributed to the effects of poor lifestyle habits …

Statins are commonly prescribed medications widely investigated for their potential actions
on the brain and mental health. Pre-clinical and clinical evidence suggests that statins may …

Mental disorders are highly comorbid and occur together with physical diseases, which are
often considered to arise from separate pathogenic pathways. We observed in alcohol …

Cognitive processes, particularly learning and memory, are crucial brain mechanisms
mediating the successful adaptation of individuals to constantly changing environmental …

Patients with cancer are at greater risk of developing depression in comparison to the
general population and this is associated with serious adverse effects, such as poorer …

Background The association between abnormal gut microbiome composition and
depression is well established. However, the composition and functional capacity of the gut …

Background: Depression is a leading cause of disability, burdened by high levels of non-
response to conventional antidepressants. Novel therapeutic strategies targeting non …