Copper homeostasis and cuproptosis in health and disease
L Chen, J Min, F Wang - Signal transduction and targeted therapy, 2022 - nature.com
As an essential micronutrient, copper is required for a wide range of physiological processes
in virtually all cell types. Because the accumulation of intracellular copper can induce …
in virtually all cell types. Because the accumulation of intracellular copper can induce …
Targeting ferroptosis opens new avenues for the development of novel therapeutics
S Sun, J Shen, J Jiang, F Wang, J Min - Signal transduction and …, 2023 - nature.com
Ferroptosis is an iron-dependent form of regulated cell death with distinct characteristics,
including altered iron homeostasis, reduced defense against oxidative stress, and abnormal …
including altered iron homeostasis, reduced defense against oxidative stress, and abnormal …
Mitochondria-associated programmed cell death as a therapeutic target for age-related disease
Mitochondria, ubiquitous double-membrane-bound organelles, regulate energy production,
support cellular activities, harbor metabolic pathways, and, paradoxically, mediate cell fate …
support cellular activities, harbor metabolic pathways, and, paradoxically, mediate cell fate …
Fighting age-related orthopedic diseases: focusing on ferroptosis
Q Ru, Y Li, W Xie, Y Ding, L Chen, G Xu, Y Wu… - Bone research, 2023 - nature.com
Ferroptosis, a unique type of cell death, is characterized by iron-dependent accumulation
and lipid peroxidation. It is closely related to multiple biological processes, including iron …
and lipid peroxidation. It is closely related to multiple biological processes, including iron …
N6-Methyladenosine-modified circSAV1 triggers ferroptosis in COPD through recruiting YTHDF1 to facilitate the translation of IREB2
H Xia, Y Wu, J Zhao, C Cheng, J Lin, Y Yang… - Cell Death & …, 2023 - nature.com
Epithelial cell damage-initiated chronic obstructive pulmonary disease (COPD) is implicated
in regulated cell death (RCD) including ferroptosis triggered by complex gene-environment …
in regulated cell death (RCD) including ferroptosis triggered by complex gene-environment …
Targeting epigenetic and posttranslational modifications regulating ferroptosis for the treatment of diseases
Y Wang, J Hu, S Wu, JS Fleishman, Y Li, Y Xu… - … and Targeted Therapy, 2023 - nature.com
Ferroptosis, a unique modality of cell death with mechanistic and morphological differences
from other cell death modes, plays a pivotal role in regulating tumorigenesis and offers a …
from other cell death modes, plays a pivotal role in regulating tumorigenesis and offers a …
Ionizing radiation-induced mitophagy promotes ferroptosis by increasing intracellular free fatty acids
P Yang, J Li, T Zhang, Y Ren, Q Zhang, R Liu… - Cell Death & …, 2023 - nature.com
Ferroptosis is a type of cell death characterized by the accumulation of intracellular iron and
an increase in hazardous lipid peroxides. Ferroptosis and autophagy are closely related …
an increase in hazardous lipid peroxides. Ferroptosis and autophagy are closely related …
Malic enzyme 1 as a novel anti‐ferroptotic regulator in hepatic ischemia/reperfusion injury
X Fang, J Zhang, Y Li, Y Song, Y Yu, Z Cai… - Advanced …, 2023 - Wiley Online Library
Ferroptosis has been linked to the pathogenesis of hepatic injury induced by
ischemia/reperfusion (I/R). However, the mechanistic basis remains unclear. In this study, by …
ischemia/reperfusion (I/R). However, the mechanistic basis remains unclear. In this study, by …
Tactile Sensors: Hydroxyl Decorated Silver Metal–Organic Frameworks for Detecting Cr2O72–, MnO4–, Humic Acid, and Fe3+ Ions
Anionic, acidic, and metal ions are common contaminants in water and cause serious
concerns for human and aquatic life. With the goal of rapid detection of analytes, we herein …
concerns for human and aquatic life. With the goal of rapid detection of analytes, we herein …
Targeting ferroptosis by poly(acrylic) acid coated Mn3O4 nanoparticles alleviates acute liver injury
X Shan, J Li, J Liu, B Feng, T Zhang, Q Liu… - Nature …, 2023 - nature.com
Ferroptosis, a newly characterized form of regulated cell death, is induced by excessive
accumulation of lipid peroxidation catalyzed by intracellular bioactive iron. Increasing …
accumulation of lipid peroxidation catalyzed by intracellular bioactive iron. Increasing …