This review highlights the advantages of high-precision liquid chromatography with an
electrochemical detector (HPLC-ECD) in detecting and quantifying biological samples …

Secoiridoids are natural products of cyclopentane monoterpene derivatives that are formed
by splitting the rings of cyclomethene oxime compounds at C‐7 and C‐8, and only account …

This study was conducted to compare the synbiotic activity between Corni fructus (C. fructus)
and Limosilactobacillus reuteri (L. reuteri) on dextran sulfate sodium (DSS)-induced colitis …

Sweroside is a secoiridoid glycoside and belongs to a large group of naturally occurring
monoterpenes with glucose sugar attached to C-1 in the pyran ring. Sweroside can promote …

A novel series of phthalimide-hydroxypyridinone derivatives were rationally designed and
evaluated as potential anti-Alzheimer's disease (AD) agents. Bioactivity tests showed that all …

This study aimed to develop novel rapid-acting antidepressants with sustained efficacy and
favorable safety profiles. We designed and synthesized a series of fluorine-containing …

Age-related neurodegenerative diseases accompanied by learning and memory deficits are
growing in prevalence due to population aging. Cellular oxidative stress is a common …

Anti‐Alzheimer's disease (AD) drugs can only change the symptoms of cognitive impairment
in a short time but cannot prevent or completely cure AD. Thus, a more effective drug is …

Vascular dementia (VaD) is associated with cerebral hypoperfusion, which results in long-
term cognitive impairment and memory loss. Cornel iridoid glycoside (CIG) is the major …

Four previously undescribed iridoid glycosides neocornuside A–D (1–4), along with six
known ones (5–10), were isolated from Cornus officinalis fruit. Their structures were …