G protein-coupled receptor (GPCR) family members can sense an extraordinary variety of
biomolecules to activate intracellular signalling cascades that modulate key aspects of cell …

Regulator of G protein signaling 6 (RGS6) is unique among the members of the RGS protein
family as it remains the only protein with the demonstrated capacity to control G protein …

In addition to its critical role in lysosomes for catabolism of sialoglycoconjugates, NEU1 is
expressed at the plasma membrane and regulates a myriad of receptors by desialylation …

GABAB receptors are the G-protein coupled receptors for the main inhibitory
neurotransmitter in the brain, GABA. GABAB receptors were shown to associate with homo …

The molecular components of store-operated Ca2+ influx channels (SOCs) in proliferative
and migratory vascular smooth muscle cells (VSMCs) are quite intricate with many channels …

The orexin 1 receptor (OX1R) and the kappa opioid receptor (KOR) are two G protein-
coupled receptors (GPCRs) previously demonstrated to play important roles in modulating …

Caveolins have been recognized over the past few decades as key regulators of cell
physiology. They are ubiquitously expressed and regulate a number of processes that …

A variety of metabolic disease states as well as the ageing process are characterised with a
state of low-gradechronic inflammation, which may contribute to skeletal muscle wasting …

Transmembrane signal transduction by ligand-activated G protein-coupled receptors
(GPCRs) controls virtually every aspect of mammalian physiology, and this receptor class is …

La mélatonine est une neuro-hormone secrétée par la glande pinéale pour réguler les
rythmes circadiens, le sommeil, la physiologie de la rétine, la reproduction saisonnière et …