Head and neck cancer
Most head and neck cancers are squamous cell carcinomas that develop in the upper
aerodigestive epithelium after exposure to carcinogens such as tobacco and alcohol …
aerodigestive epithelium after exposure to carcinogens such as tobacco and alcohol …
Molecular pathology of head and neck cancer: implications for diagnosis, prognosis, and treatment
The prototypic head and neck squamous cell carcinoma (HNSCC) arises from the mucosal
lining of the upper aerodigestive tract, demonstrates squamous differentiation …
lining of the upper aerodigestive tract, demonstrates squamous differentiation …
Randomized phase III trial of concurrent accelerated radiation plus cisplatin with or without cetuximab for stage III to IV head and neck carcinoma: RTOG 0522
KK Ang, Q Zhang, DI Rosenthal… - Journal of clinical …, 2014 - ascopubs.org
Purpose Combining cisplatin or cetuximab with radiation improves overall survival (OS) of
patients with stage III or IV head and neck carcinoma (HNC). Cetuximab plus platinum …
patients with stage III or IV head and neck carcinoma (HNC). Cetuximab plus platinum …
Randomized phase III trial to test accelerated versus standard fractionation in combination with concurrent cisplatin for head and neck carcinomas in the Radiation …
PF Nguyen-Tan, Q Zhang, KK Ang… - Journal of Clinical …, 2014 - ascopubs.org
Purpose We tested the efficacy and toxicity of cisplatin plus accelerated fractionation with a
concomitant boost (AFX-C) versus standard fractionation (SFX) in locally advanced head …
concomitant boost (AFX-C) versus standard fractionation (SFX) in locally advanced head …
Safety and efficacy of pembrolizumab with chemoradiotherapy in locally advanced head and neck squamous cell carcinoma: a phase IB study
SF Powell, KA Gold, MM Gitau, CJ Sumey… - Journal of Clinical …, 2020 - ascopubs.org
PURPOSE Pembrolizumab is a humanized monoclonal antibody that blocks interaction
between programmed death receptor-1 (PD-1) and its ligands (PD-L1, PD-L2). Although …
between programmed death receptor-1 (PD-1) and its ligands (PD-L1, PD-L2). Although …
Head and neck cancer: an evolving treatment paradigm
DM Cognetti, RS Weber, SY Lai - Cancer, 2008 - Wiley Online Library
Since the inception of this journal in 1948, the understanding of etiologic factors that
contribute to and the treatment of head and neck cancer has evolved dramatically. Advances …
contribute to and the treatment of head and neck cancer has evolved dramatically. Advances …
Introducing a new entity: chemotherapy-induced arrhythmia
M Guglin, M Aljayeh, S Saiyad, R Ali, AB Curtis - Europace, 2009 - academic.oup.com
The relationship between chemotherapy and arrhythmias has not been well established. We
reviewed the existing literature to better understand this connection. We reviewed published …
reviewed the existing literature to better understand this connection. We reviewed published …
The chemoradiation paradigm in head and neck cancer
TY Seiwert, JK Salama, EE Vokes - Nature clinical practice Oncology, 2007 - nature.com
In this article, we use the example of head and neck cancer to show how concurrent
chemoradiotherapy is used to treat a cancer where locoregional control is central for …
chemoradiotherapy is used to treat a cancer where locoregional control is central for …
Structural characterization of N-linked oligosaccharides on monoclonal antibody cetuximab by the combination of orthogonal matrix-assisted laser desorption …
J Qian, T Liu, L Yang, A Daus, R Crowley, Q Zhou - Analytical biochemistry, 2007 - Elsevier
Cetuximab is a novel therapeutic monoclonal antibody with two N-glycosylation sites: a
conserved site in the CH2 domain and a second site within the framework 3 of the variable …
conserved site in the CH2 domain and a second site within the framework 3 of the variable …
Treatment of nasal cavity and paranasal sinus cancer with modern radiotherapy techniques in the postoperative setting—the MSKCC experience
BS Hoppe, LD Stegman, MJ Zelefsky… - International Journal of …, 2007 - Elsevier
Purpose: To perform a retrospective analysis of patients with paranasal sinus (PNS) cancer
treated with postoperative radiotherapy (RT) at Memorial Sloan-Kettering Cancer Center …
treated with postoperative radiotherapy (RT) at Memorial Sloan-Kettering Cancer Center …