The risks associated with use of antiepileptic drugs during pregnancy are a major concern
for all women with epilepsy with childbearing potential. These risks have to be balanced …

One-carbon metabolism involving the folate and methionine cycles integrates nutritional
status from amino acids, glucose and vitamins, and generates diverse outputs, such as the …

This is an update of the Norwegian Mother and Child Cohort Study (MoBa) cohort profile
which was published in 2006. Pregnant women attending a routine ultrasound examination …

Hyperhomocysteinemia is recognized as a risk factor for several diseases, including
cardiovascular and neurological conditions. Homocysteine (HCys) is a key metabolite …

Background Many women of childbearing potential take antiepileptic drugs, but the cognitive
effects of fetal exposure are uncertain. We aimed to assess effects of commonly used …

Background: Over the past 10 years, research into environmental risk factors for autism has
grown dramatically, bringing evidence that an array of non-genetic factors acting during the …

Importance Prenatal folic acid supplements reduce the risk of neural tube defects in children,
but it has not been determined whether they protect against other neurodevelopmental …

Autism is a developmental disability with age of onset in childhood (under 3 years old),
which is characterized by definite impairments in social interactions, abnormalities in …

Current understanding of biologic processes indicates that women's nutritional status before
and during early pregnancy may play an important role in determining early developmental …

OBJECTIVES: Results of animal studies suggest that maternal immune activation during
pregnancy causes deficiencies in fetal neurodevelopment. Infectious disease is the most …