Inhalable particulate drug delivery systems for lung cancer therapy: Nanoparticles, microparticles, nanocomposites and nanoaggregates
There is progressive evolution in the use of inhalable drug delivery systems (DDSs) for lung
cancer therapy. The inhalation route offers many advantages, being non-invasive method of …
cancer therapy. The inhalation route offers many advantages, being non-invasive method of …
The progress and promise of RNA medicine─ an arsenal of targeted treatments
In the past decade, there has been a shift in research, clinical development, and commercial
activity to exploit the many physiological roles of RNA for use in medicine. With the rapid …
activity to exploit the many physiological roles of RNA for use in medicine. With the rapid …
[HTML][HTML] Insight into the prospects for RNAi therapy of cancer
Z Tian, G Liang, K Cui, Y Liang, Q Wang, S Lv… - Frontiers in …, 2021 - frontiersin.org
RNA interference (RNAi), also known as gene silencing, is a biological process that
prevents gene expression in certain diseases such as cancer. It can be used to improve the …
prevents gene expression in certain diseases such as cancer. It can be used to improve the …
Engineered extracellular vesicles with synthetic lipids via membrane fusion to establish efficient gene delivery
YY Jhan, D Prasca-Chamorro, GP Zuniga… - International journal of …, 2020 - Elsevier
The low yield of extracellular vesicle (EV) secretion is a major obstacle for mass production
and limits their potential for clinical applications as a drug delivery platform. Here, we mass …
and limits their potential for clinical applications as a drug delivery platform. Here, we mass …
Gold nanoparticles in microelectronics advancements and biomedical applications
MM Ghobashy, SA Alkhursani, HA Alqahtani… - Materials Science and …, 2024 - Elsevier
Gold nanoparticles (AuNPs) possess unique size-dependent optical, electronic, and
chemical properties, making them auspicious and tunable nanoscale building blocks for …
chemical properties, making them auspicious and tunable nanoscale building blocks for …
Induction of virus resistance by exogenous application of double-stranded RNA
Highlights•Exogenous application of dsRNA can induce antiviral silencing in plants.•Naked
dsRNA on leaves affords virus protection only up to 5 days postspray.•Nanoparticle …
dsRNA on leaves affords virus protection only up to 5 days postspray.•Nanoparticle …
Nanoparticles for local delivery of siRNA in lung therapy
M Kubczak, S Michlewska, M Bryszewska… - Advanced Drug Delivery …, 2021 - Elsevier
An overview of the application of natural and synthetic, non-viral vectors for oligonucleotide
delivery into the lung is presented in this review, with a special focus on lung cancer. Due to …
delivery into the lung is presented in this review, with a special focus on lung cancer. Due to …
Current updates of CRISPR/Cas9‐mediated genome editing and targeting within tumor cells: an innovative strategy of cancer management
Clustered regularly interspaced short palindromic repeats‐associated protein
(CRISPR/Cas9), an adaptive microbial immune system, has been exploited as a robust …
(CRISPR/Cas9), an adaptive microbial immune system, has been exploited as a robust …
[HTML][HTML] Potential applications of nanoparticles in improving the outcome of lung cancer treatment
A Girigoswami, K Girigoswami - Genes, 2023 - mdpi.com
Lung cancer is managed using conventional therapies, including chemotherapy, radiation
therapy, or a combination of both. Each of these therapies has its own limitations, such as …
therapy, or a combination of both. Each of these therapies has its own limitations, such as …
[HTML][HTML] The nanopharmacology and nanotoxicology of nanomaterials: new opportunities and challenges
A Radomska, J Leszczyszyn… - Advances in Clinical …, 2016 - advances.umw.edu.pl
The very dynamic growth of nanotechnology, nanomaterials (sized 1–100 nm) and their
medical applications over the past 10 years has promised to add a new impetus to the …
medical applications over the past 10 years has promised to add a new impetus to the …