Nanotherapeutics have improved the quality of life of cancer patients, primarily by reducing
the adverse effects of chemotherapeutic agents, but improvements in overall survival are …

Polymeric nanocarriers (PNs) have demonstrated to be a promising alternative to treat
intracellular infections. They have outstanding performance in delivering antimicrobials …

Antibiotics target conserved bacterial cellular pathways or growth functions and therefore
cannot selectively kill specific members of a complex microbial population. Here, we …

Size, surface charge, and material compositions are known to influence cell uptake of
nanoparticles. However, the effect of particle geometry, ie, the interplay between nanoscale …

Oral administration is the preferred route of drug delivery in clinical practice due to its
noninvasiveness, safety, convenience, and high patient compliance. The gastrointestinal …

Physiological characteristics of diseases bring about both challenges and opportunities for
targeted drug delivery. Various drug delivery platforms have been devised ranging from …

Targeted nanomedicine holds promise to find clinical use in many medical areas.
Endothelial cells that line the luminal surface of blood vessels represent a key target for …

Efficient penetration and uniform distribution of nanoparticles (NPs) inside solid tissues and
tumors is paramount to their therapeutic and diagnostic success. While many studies have …

Insufficient data on nano-and microplastics (NMP) hinder robust evaluation of their potential
health risks. Methodological disparities and the absence of established toxicity thresholds …

Gene therapy, a therapeutic approach based on nucleotide delivery to the targeted cells,
serves as a hot spot research. Regardless of recent developments in various nucleotide …