Genetic testing is used widely for diagnostic, carrier and predictive testing in monogenic
diseases. Until recently, there were no genetic testing options available for multifactorial …

Clinical use of polygenic risk scores (PRS) will look very different to the more familiar
monogenic testing. Here we argue that despite these differences, most of the ethical, legal …

The discovery of genes underlying inherited predisposition to breast and ovarian cancer has
revolutionized the ability to identify women at high risk for these diseases before they …

Limited translational genomic research data have been reported on the application of
exome sequencing and parallel gene testing for preconception carrier screening (PCS) …

Purpose Prenatal genetic carrier screening can identify parents at risk of having a child
affected by a recessive condition. However, the conditions/genes most appropriate for …

We sought to explore individuals' motivations for using their direct-to-consumer genetic
testing data to generate polygenic risk scores (PRSs) using a not-for-profit third-party tool …

We surveyed 488 primary care providers in community and academic practices in New York
City in the period 2014–16 about their views on genetic testing for chronic diseases. The …

The latest response to consumers' increased demand for accessible genetic health
information is the US Food and Drug Administration (FDA)'s recent approval of 23andMe's …

As the public's interest in genetics and genomics has increased, there has been
corresponding and unprecedented growth in direct‐to‐consumer genetic testing (DTC‐GT) …

In this paper we explore a new technological intersection in the “big data revolution”: the
integration of two forms of data, genetic data and fitness tracking data. For example, a small …