In 2019, the novel coronavirus, SARS-CoV-2, caused a worldwide pandemic, affecting more
than 630 million individuals and causing 6.5 million deaths. In the general population …

Introduction With a growing knowledge of Inborn errors immunity (IEI), immunological
profiling and genetic predisposition to IEI phenocopies have been developed in recent …

While SARS-CoV-2 infection causes a mild disease in most children, SARS-CoV-2 infection
may be lethal in a few of them. In the defense against SARS-CoV-2, type I interferons are …

Background Debates on the allocation of medical resources during the coronavirus disease
2019 (COVID-19) pandemic revealed the need for a better understanding of immunological …

Background The CDC and ACIP recommend COVID-19 vaccination for patients with inborn
errors of immunity (IEI). Not much is known about vaccine safety in IEI, and whether …

There is growing evidence to suggest that severe disease in children infected with common
viruses that are typically benign in other children can result from inborn errors of immunity or …

Background Inborn errors of immunity (IEIs) are considered significant challenges for
children with IEIs, their families, and their medical providers. Infections are the most common …

Purpose To describe SARS-CoV-2 infection outcome in unvaccinated children and young
adults with inborn errors of immunity (IEI) and to compare their specific acute and long-term …

SARS‐CoV‐2 causes millions of infection cases and coronavirus disease 2019 (COVID‐19)‐
related deaths worldwide. In addition to acute illnesses, children and adolescents suffer from …

Purpose: Case reports of the development of perimyocarditis in adolescents and young
adults after BNT162b2 messenger RNA (mRNA) COVID-19 vaccination have raised …