Binge eating disorder (BED) is characterized by regular binge eating episodes during which
individuals ingest comparably large amounts of food and experience loss of control over …

The peripheral peptide hormone ghrelin is a powerful stimulator of food intake, which leads
to body weight gain and adiposity in both rodents and humans. The hormone, thus …

The melanocortinergic neural circuit, known for its influence on energy expenditure and
feeding behavior, also plays a role in stress and stress-induced psychiatric disorders …

The melanocortins are derived from proopiomelanocortin (POMC) and include three forms of
melanocyte-stimulating hormone (α-, β-, γ-, MSH) and adrenocorticotropic hormone. α-MSH …

Obesity and eating disorders are conditions that involve eating behaviors and are
sometimes comorbid. Current evidence supports alterations in immunoinflammatory …

Nociceptin/orphanin FQ (N/OFQ) is a 17-residue neuropeptide that binds the nociceptin
opioid-like receptor (NOP). N/OFQ exhibits nucleotidic and aminoacidics sequence …

Orexin‐A and orexin‐B, also named hypocretin‐1 and hypocretin‐2, are two hypothalamic
neuropeptides highly conserved across mammalian species. Their effects are mediated by …

The reward system involved in hedonic food intake presents neuronal and behavioral
dysregulations during obesity. Moreover, gut microbiota dysbiosis during obesity promotes …

Background: Sleep problems and eating disorders (EDs) are both serious public health
concerns often seen in young adults. Yet, the underlying mechanisms for such associations …

Background Melanocortin-4 receptor (MC4R) mutations are the most common of the rare
monogenic forms of obesity. However, the efficacy of bariatric surgery (BS) and …