Macrophage-mediated inflammation in skin wound healing

A Hassanshahi, M Moradzad, S Ghalamkari, M Fadaei… - Cells, 2022 - mdpi.com
Macrophages are key immune cells that respond to infections, and modulate
pathophysiological conditions such as wound healing. By possessing phagocytic activities …

Curcumin as an anti‐inflammatory agent: Implications to radiotherapy and chemotherapy

B Farhood, K Mortezaee, NH Goradel… - Journal of cellular …, 2019 - Wiley Online Library
Cancer is the second cause of death worldwide. Chemotherapy and radiotherapy are the
most common modalities for the treatment of cancer. Experimental studies have shown that …

Adipose‐derived stem cells for wound healing

A Hassanshahi, M Hassanshahi… - Journal of cellular …, 2019 - Wiley Online Library
Wound healing is a complex but a fine‐tuned biological process in which human skin has
the ability to regenerate itself following damage. However, in particular conditions such as …

[HTML][HTML] Apelin+ endothelial niche cells control hematopoiesis and mediate vascular regeneration after myeloablative injury

Q Chen, Y Liu, HW Jeong, M Stehling, B Zhou… - Cell stem cell, 2019 - cell.com
Radiotherapy and chemotherapy disrupt bone vasculature, but the underlying causes and
mechanisms enabling vessel regeneration after bone marrow (BM) transplantation remain …

Exploring and analyzing the systemic delivery barriers for nanoparticles

L Wang, S Quine, AN Frickenstein… - Advanced Functional …, 2024 - Wiley Online Library
Most nanomedicines require efficient in vivo delivery to elicit meaningful diagnostic and
therapeutic effects. However, en route to their intended tissues, systemically administered …

[HTML][HTML] Piezo1-mediated mechanosensation in bone marrow macrophages promotes vascular niche regeneration after irradiation injury

X Zhang, L Hou, F Li, W Zhang, C Wu, L Xiang, J Li… - Theranostics, 2022 - ncbi.nlm.nih.gov
Background: Irradiation disrupts the vascular niche where hematopoietic stem cells (HSCs)
reside, causing delayed hematopoietic reconstruction. The subsequent recovery of …

VEGF-C protects the integrity of the bone marrow perivascular niche in mice

S Fang, S Chen, H Nurmi, VM Leppänen… - Blood, The Journal …, 2020 - ashpublications.org
Hematopoietic stem cells (HSCs) reside in the bone marrow (BM) stem cell niche, which
provides a vital source of HSC regulatory signals. Radiation and chemotherapy disrupt the …

Type H vessel/platelet‐derived growth factor receptor β+ perivascular cell disintegration is involved in vascular injury and bone loss in radiation‐induced bone …

J Li, X Chen, L Ren, X Chen, T Wu, Y Wang… - Cell …, 2023 - Wiley Online Library
Collapse of the microvascular system is a prerequisite for radiation‐induced bone loss.
Since type H vessels, a specific bone vessel subtype surrounded by platelet‐derived growth …

RETRACTED ARTICLE: Schnurri-3 regulates BMP9-induced osteogenic differentiation and angiogenesis of human amniotic mesenchymal stem cells through Runx2 …

Y Li, Z Liu, Y Tang, W Feng, C Zhao, J Liao… - Cell death & …, 2020 - nature.com
Human amniotic mesenchymal stem cells (hAMSCs) are multiple potent progenitor cells
(MPCs) that can differentiate into different lineages (osteogenic, chondrogenic, and …

PEDF promotes the repair of bone marrow endothelial cell injury and accelerates hematopoietic reconstruction after bone marrow transplantation

W Ju, W Lu, L Ding, Y Bao, F Hong, Y Chen… - Journal of Biomedical …, 2020 - Springer
Background Preconditioning before bone marrow transplantation such as irradiation causes
vascular endothelial cells damage and promoting the repair of damaged endothelial cells is …