[HTML][HTML] Polyphenols inhibiting MAPK signalling pathway mediated oxidative stress and inflammation in depression

T Behl, T Rana, GH Alotaibi, M Shamsuzzaman… - Biomedicine & …, 2022 - Elsevier
Depression is one of the most debilitating psychiatric disorders affecting people of all ages
worldwide. Despite significant heterogeneity between studies, increased inflammation and …

Flavonoids: classification, function, and molecular mechanisms involved in bone remodelling

P Ramesh, R Jagadeesan, S Sekaran… - Frontiers in …, 2021 - frontiersin.org
Flavonoids are polyphenolic compounds spotted in various fruits, vegetables, barks, tea
plants, and stems and many more natural commodities. They have a multitude of …

Dietary polyphenols suppress chronic inflammation by modulation of multiple inflammation-associated cell signaling pathways

I Jantan, MA Haque, L Arshad, H Harikrishnan… - The Journal of nutritional …, 2021 - Elsevier
The high failure rate of the reductionist approach to discover effective and safe drugs to treat
chronic inflammatory diseases has led scientists to seek alternative ways. Recently …

Kaempferol–A dietary anticancer molecule with multiple mechanisms of action: Recent trends and advancements

D Kashyap, A Sharma, HS Tuli, K Sak, S Punia… - Journal of functional …, 2017 - Elsevier
The consumption of diet-based naturally bioactive metabolites is preferred to synthetic
material in order to avert health-associated disorders. Among the plant-derived polyphenols …

Flavonoids in modulation of cell survival signalling pathways

ML Mansuri, P Parihar, I Solanki, MS Parihar - Genes & nutrition, 2014 - Springer
Flavonoids, a family of polyphenols, generally found in various fruits and vegetables, as well
as in many plant beverages such as tea, pomegranate juice, raspberry, blueberries, and red …

Kaempferol attenuates ROS-induced hemolysis and the molecular mechanism of its induction of apoptosis on bladder cancer

P Wu, X Meng, H Zheng, Q Zeng, T Chen, W Wang… - Molecules, 2018 - mdpi.com
Bladder cancer has become the most common malignant urinary carcinoma. Studies have
shown that significant antioxidant and bladder cancer-fighting properties of several plant …

Kaempferol attenuates hyperglycemia-induced cardiac injuries by inhibiting inflammatory responses and oxidative stress

X Chen, J Qian, L Wang, J Li, Y Zhao, J Han, Z Khan… - Endocrine, 2018 - Springer
Purpose Suppression of inflammation and oxidative stress is an attractive strategy to against
diabetic cardiomyopathy (DCM). Kaempferol (KPF) exerts both anti-inflammatory and …

Metabolomic profiling of the phytomedicinal constituents of Carica papaya L. leaves and seeds by 1H NMR spectroscopy and multivariate statistical analysis

N Gogna, N Hamid, K Dorai - Journal of pharmaceutical and biomedical …, 2015 - Elsevier
Extracts from the Carica papaya L. plant are widely reported to contain metabolites with
antibacterial, antioxidant and anticancer activity. This study aims to analyze the metabolic …

Activity of Antioxidants from Crocus sativus L. Petals: Potential Preventive Effects towards Cardiovascular System

K Zeka, P Marrazzo, M Micucci, KC Ruparelia… - Antioxidants, 2020 - mdpi.com
The petals of the saffron crocus (Crocus sativus L.) are considered a waste material in
saffron production, but may be a sustainable source of natural biologically active substances …

A bioinformatics and transcriptomics based investigation reveals an inhibitory role of Huanglian-Renshen-Decoction on hepatic glucose production of T2DM mice via …

F Wu, Q Shao, Q Xia, M Hu, Y Zhao, D Wang, K Fang… - Phytomedicine, 2021 - Elsevier
Background Excessive hepatic glucose production (HGP) largely promotes the development
of type 2 diabetes mellitus (T2DM), and the inhibition of HGP significantly ameliorates T2DM …