Metabolic syndrome and cardiovascular diseases: Going beyond traditional risk factors

JL Silveira Rossi, SM Barbalho… - Diabetes/metabolism …, 2022 - Wiley Online Library
Metabolic syndrome (MS) is a chronic non‐infective syndrome characterised clinically by a
set of vascular risk factors that include insulin resistance, hypertension, abdominal obesity …

[HTML][HTML] Ultra-processed foods and cardiovascular diseases: potential mechanisms of action

F Juul, G Vaidean, N Parekh - Advances in Nutrition, 2021 - Elsevier
Ultra-processed foods are industrially manufactured ready-to-eat or ready-to-heat
formulations containing food additives and little or no whole foods, in contrast to processed …

[HTML][HTML] Beyond hemostasis: platelet innate immune interactions and thromboinflammation

J Mandel, M Casari, M Stepanyan, A Martyanov… - International journal of …, 2022 - mdpi.com
There is accumulating evidence that platelets play roles beyond their traditional functions in
thrombosis and hemostasis, eg, in inflammatory processes, infection and cancer, and that …

Innate immune receptors in platelets and platelet-leukocyte interactions

PRB Dib, AC Quirino-Teixeira, LB Merij… - Journal of Leucocyte …, 2020 - academic.oup.com
Platelets are chief cells in hemostasis. Apart from their hemostatic roles, platelets are major
inflammatory effector cells that can influence both innate and adaptive immune responses …

[HTML][HTML] Renin-angiotensin system in pathogenesis of atherosclerosis and treatment of CVD

AV Poznyak, D Bharadwaj, G Prasad… - International Journal of …, 2021 - mdpi.com
Atherosclerosis has complex pathogenesis, which involves at least three serious aspects:
inflammation, lipid metabolism alterations, and endothelial injury. There are no effective …

Platelet activation and prothrombotic mediators at the nexus of inflammation and atherosclerosis: Potential role of antiplatelet agents

R Lordan, A Tsoupras, I Zabetakis - Blood reviews, 2021 - Elsevier
Platelets are central to inflammation-related manifestations of cardiovascular diseases
(CVD) such as atherosclerosis. Platelet-activating factor (PAF), thrombin, thromboxane A 2 …

[HTML][HTML] RETRACTED ARTICLE: Circular RNA circ_0003204 inhibits proliferation, migration and tube formation of endothelial cell in atherosclerosis via miR-370-3p …

S Zhang, G Song, J Yuan, S Qiao, S Xu, Z Si… - Journal of Biomedical …, 2020 - Springer
Abstract Background Circular RNAs (circRNAs) represent a class of non-coding RNAs
(ncRNAs) which are widely expressed in mammals and tissue-specific, of which some could …

[HTML][HTML] ADMA: a key player in the relationship between vascular dysfunction and inflammation in atherosclerosis

L Dowsett, E Higgins, S Alanazi… - Journal of Clinical …, 2020 - mdpi.com
Atherosclerosis is a chronic cardiovascular disease which increases risk of major
cardiovascular events including myocardial infarction and stroke. Elevated plasma …

Targeting endothelial vascular cell adhesion molecule-1 in atherosclerosis: drug discovery and development of vascular cell adhesion molecule-1–directed novel …

JR Pickett, Y Wu, LF Zacchi, HT Ta - Cardiovascular Research, 2023 - academic.oup.com
Vascular cell adhesion molecule-1 (VCAM-1) has been well established as a critical
contributor to atherosclerosis and consequently as an attractive therapeutic target for anti …

The inflammatory potential of the diet as a link between food processing and low-grade inflammation: An analysis on 21,315 participants to the Moli-sani study

C Mignogna, S Costanzo, A Di Castelnuovo… - Clinical Nutrition, 2022 - Elsevier
Background & aims Food processing may adversely affect human health through a variety of
mechanisms, including the development of a chronic pro-inflammatory state. In this study we …