Long non-coding RNAs (lncRNAs) are recently-discovered transcripts that regulate vital
cellular processes and are crucially connected to diseases. Despite their unprecedented …

High-speed atomic force microscopy (HS-AFM) allows direct observation of biological
molecules in dynamic action. However, HS-AFM has no atomic resolution. This article …

Atomic force microscopy (AFM) can visualize the dynamics of single biomolecules under
near-physiological conditions. However, the scanning tip probes only the molecular surface …

Observing the structural dynamics of biomolecules is vital to deepening our understanding
of biomolecular functions. High-speed (HS) atomic force microscopy (AFM) is a powerful …

Although controversial, the amyloid cascade hypothesis remains central to the Alzheimer's
disease (AD) field and posits amyloid‐beta (Aβ) as the central factor initiating disease onset …

The structural and dynamical characterization of biomolecules holds central importance in
the endeavor to understand the molecular mechanisms regulating living systems. However …

Atomic force microscopy (AFM) can visualize functional biomolecules near the physiological
condition, but the observed data are limited to the surface height of specimens. Since the …

High-speed atomic force microscopy (HS-AFM) is a powerful technique for capturing the
time-resolved behavior of biomolecules. However, structural information in HS-AFM images …

ClpB belongs to the cellular disaggretase machinery involved in rescuing misfolded or
aggregated proteins during heat or other cellular shocks. The function of this protein relies …

Abstract Analysis of virus-like particles (VLPs) is an essential task in optimizing their
implementation as vaccine antigens for virus-initiated diseases. Interrogating VLP …