Gap junctions allow the exchange of ions, second messengers, and small metabolites
between adjacent cells and are formed by two unrelated protein families, the pannexins and …

Cxs (connexins), the protein subunits forming gap junction intercellular communication
channels, are transported to the plasma membrane after oligomerizing into hexameric …

Naturally occurring regulatory T cells (T reg cells) are a thymus-derived subset of T cells,
which are crucial for the maintenance of peripheral tolerance by controlling potentially …

Recreating the structure of human tissues in the laboratory is valuable for fundamental
research, testing interventions, and reducing the use of animals. Critical to the use of such …

Hepatitis C virus (HCV) infection is the major risk factor for liver cirrhosis and hepatocellular
carcinoma (HCC). The mechanisms of HCC initiation, growth, and metastasis appear to be …

Simple Summary This paper summarizes the crosstalk between tumor/non-tumor cells and
other elements of the glioblastoma (GB) microenvironment. In tumor pathology, glial cells …

Connexins constitute a large family of trans-membrane proteins that allow intercellular
communication and the transfer of ions and small signaling molecules between cells …

Inside cells, the endoplasmic reticulum (ER) forms the largest Ca 2+ store. Ca 2+ is actively
pumped by the SERCA pumps in the ER, where intraluminal Ca 2+-binding proteins enable …

The pannexin proteins represent a new gap junction family. However, the cellular functions
of pannexins remain largely unknown. Here, we demonstrate that pannexin 3 (Panx3) …

Congenital cataracts, the most common cause of visual impairment and blindness in
children worldwide, have diverse etiologies. According to statistics analysis, about one …