[HTML][HTML] Meiosis: dances between homologs

D Zickler, N Kleckner - Annual Review of Genetics, 2023 - annualreviews.org
The raison d'être of meiosis is shuffling of genetic information via Mendelian segregation
and, within individual chromosomes, by DNA crossing-over. These outcomes are enabled …

Disparate roles for C. elegans DNA translocase paralogs RAD-54.L and RAD-54.B in meiotic prophase germ cells

K Yamaya, B Wang, N Memar, AS Odiba… - Nucleic Acids …, 2023 - academic.oup.com
RAD54 family DNA translocases partner with RAD51 recombinases to ensure stable
genome inheritance, exhibiting biochemical activities both in promoting recombinase …

Rad53 regulates the lifetime of Rdh54 at homologous recombination intermediates

J Hu, B Ferlez, J Dau, JB Crickard - Nucleic Acids Research, 2023 - academic.oup.com
Rdh54 is a conserved DNA translocase that participates in homologous recombination (HR),
DNA checkpoint adaptation, and chromosome segregation. Saccharomyces cerevisiae …

Spontaneous and double-strand break repair-associated quasipalindrome and frameshift mutagenesis in budding yeast: role of mismatch repair

N Sugawara, MJ Towne, ST Lovett, JE Haber - Genetics, 2024 - academic.oup.com
Although gene conversion (GC) in Saccharomyces cerevisiae is the most error-free way to
repair double-strand breaks (DSBs), the mutation rate during homologous recombination is …

The translocation activity of Rad54 reduces crossover outcomes during homologous recombination

K Sridalla, MV Woodhouse, J Hu, J Scheer… - Nucleic Acids …, 2024 - academic.oup.com
Homologous recombination (HR) is a template-based DNA double-strand break repair
pathway that requires the selection of an appropriate DNA sequence to facilitate repair …