[HTML][HTML] Traditional Chinese medicine combined with pulmonary drug delivery system and idiopathic pulmonary fibrosis: rationale and therapeutic potential

Y Zhang, P Lu, H Qin, Y Zhang, X Sun, X Song… - Biomedicine & …, 2021 - Elsevier
Idiopathic pulmonary fibrosis (IPF) is a progressive pulmonary interstitial inflammatory
disease of unknown etiology, and is also a sequela in severe patients with the Coronavirus …

Protective effects of paeoniflorin on cardiovascular diseases: A pharmacological and mechanistic overview

X Li, C Sun, J Zhang, L Hu, Z Yu, X Zhang… - Frontiers in …, 2023 - frontiersin.org
Background and ethnopharmacological relevance: The morbidity and mortality of
cardiovascular diseases (CVDs) are among the highest of all diseases, necessitating the …

Danlou Tablet (丹蒌片) Improves Chronic Intermittent Hypoxia-induced Dyslipidemia and Arteriosclerosis by HIF-1 α-Angptl4 mRNA Signaling Pathway

J Tang, G Li, Z Liu, R Yi, D Yu, Y Zhang, S Zhao… - Chinese journal of …, 2020 - Springer
Abstract Objective To detect whether Danlou Tablet (丹蒌片, DLT) regulates the hypoxia-
induced factor (HIF)-1 α-angiopoietin-like 4 (Angptl4) mRNA signaling pathway and explore …

Development of a three-step-based novel strategy integrating DMPK with network pharmacology and bioactivity evaluation for the discovery of Q-markers of traditional …

Q Wang, G Chen, X Chen, Y Liu, Z Qin, P Lin, H Shang… - Phytomedicine, 2023 - Elsevier
Background Quality marker (Q-marker) serves an important role in promoting the
standardization of the quality of traditional Chinese medicine (TCM) prescriptions. However …

Anti-inflammatory and antioxidative effects of Dan-Lou tablets in the treatment of coronary heart disease revealed by metabolomics integrated with molecular …

Z Li, L Yang, Y Liu, H Xu, S Wang, Y Liu, H Zhao… - Journal of …, 2019 - Elsevier
Abstract Ethnopharmacological evidence The Dan-Lou tablet (DLT), a well-known Chinese
prescription, has definitive clinical efficacy in the treatment of precordial discomfort and pain …

Dan-Lou tablets reduces inflammatory response via suppression of the MyD88/p38 MAPK/NF-κB signaling pathway in RAW 264.7 macrophages induced by ox-LDL

Z Li, Q Cheng, L Yu, YY He, LN Gao, Y Wang… - Journal of …, 2022 - Elsevier
Ethnopharmacological evidence The anti-inflammatory effect of Dan-Lou tablets (DLT) have
been reported; however, the signaling pathways involved and their role in foam cell …

Ability to suppress TGF-β-activated myofibroblast differentiation distinguishes the anti-pulmonary fibrosis efficacy of two danshen-containing Chinese herbal medicine …

R Shao, F Wang, M Lyu, J Yang, P Zhang… - Frontiers in …, 2019 - frontiersin.org
Background: Idiopathic pulmonary fibrosis (IPF) is a devastating lung disease with limited
treatment options. It also leads to progressive respiratory failure, which subsequently affects …

Danlou tablet protects against cardiac remodeling and dysfunction after myocardial ischemia/reperfusion injury through activating AKT/FoxO3a pathway

L Li, W Qi, Y Zhu, M Yin, C Chen, M Wei… - Journal of …, 2023 - Springer
Myocardial ischemia/reperfusion injury (I/RI) and ventricular remodeling are the critical
pathological basis of heart failure. Danlou tablet (Dan) is a kind of Chinese patent medicine …

Traditional Chinese medicine, Danlou tablets alleviate adverse left ventricular remodeling after myocardial infarction: results of a double-blind, randomized, placebo …

S Mao, L Wang, W Ouyang, Y Zhou, J Qi, L Guo… - … and alternative medicine, 2016 - Springer
Background Danlou tablets, a patented Chinese Medicine, have been long approved for the
treatment of ischemic heart disease in China. While numerous empirical observations …

PPARγ mediates the cardioprotective roles of Danlou tablet after acute myocardial ischemia-reperfusion injury

M Wei, M Guo, X Meng, L Li, H Wang… - Frontiers in …, 2022 - frontiersin.org
Ischemic heart disease is one of the biggest threats to human life in the world. Reperfusion
therapy is an effective strategy to reduce infarct size and ischemic injury. However …