Fasciola and fasciolosis in ruminants in Europe: Identifying research needs

NJ Beesley, C Caminade, J Charlier… - Transboundary and …, 2018 - Wiley Online Library
Fasciola hepatica is a trematode parasite with a global distribution, which is responsible for
considerable disease and production losses in a range of food producing species. It is also …

Liver fluke vaccines in ruminants: strategies, progress and future opportunities

H Toet, DM Piedrafita, TW Spithill - International journal for parasitology, 2014 - Elsevier
The development of a vaccine for Fasciola spp. in livestock is a challenge and would be
advanced by harnessing our knowledge of acquired immune mechanisms expressed by …

Promising technologies in the field of helminth vaccines

DJ Perera, M Ndao - Frontiers in immunology, 2021 - frontiersin.org
Helminths contribute a larger global burden of disease than both malaria and tuberculosis.
These eukaryotes have caused human infections since before our earliest recorded history …

Efficacy of a multivalent vaccine against Fasciola hepatica infection in sheep

R Zafra, L Buffoni, R Pérez-Caballero… - Veterinary …, 2021 - Springer
In this work we report the protection found in a vaccination trial performed in sheep with two
different vaccines composed each one by a cocktail of antigens (rCL1, rPrx, rHDM and rLAP) …

QuilA® adjuvanted Coxevac® sustains Th1-CD8+-type immunity and increases protection in Coxiella burnetii-challenged goats

S Tomaiuolo, W Jansen, S Soares Martins, B Devriendt… - npj Vaccines, 2023 - nature.com
Coxevac® is the EMA-approved veterinary vaccine for the protection of cattle and goats
against Q fever, a zoonotic bacterial disease due to Coxiella burnetii. Since Coxevac® …

Arming filamentous bacteriophage, a nature-made nanoparticle, for new vaccine and immunotherapeutic strategies

R Sartorius, L D'Apice, A Prisco, P De Berardinis - Pharmaceutics, 2019 - mdpi.com
The pharmaceutical use of bacteriophages as safe and inexpensive therapeutic tools is
collecting renewed interest. The use of lytic phages to fight antibiotic-resistant bacterial …

Current status for controlling the overlooked caprine fasciolosis

G Zerna, TW Spithill, T Beddoe - Animals, 2021 - mdpi.com
Simple Summary Retaining sustainable agricultural systems is essential to feed the
expanding population. Helminth parasite infections impact livestock production values and …

[HTML][HTML] Differences in the antibody response to adult Fasciola hepatica excretory/secretory products in experimentally and naturally infected cattle and sheep

TR Walsh, S Ainsworth, S Armstrong, J Hodgkinson… - Veterinary …, 2021 - Elsevier
Fasciola hepatica (the liver fluke) is a common, global parasite of livestock. It can be highly
pathogenic and has health and welfare implications for infected individuals. Typically, in …

Autonomous Non Antioxidant Roles for Fasciola hepatica Secreted Thioredoxin-1 and Peroxiredoxin-1

A Dorey, K Cwiklinski, J Rooney… - Frontiers in cellular …, 2021 - frontiersin.org
Trematode parasites of the genus Fasciola are the cause of liver fluke disease (fasciolosis)
in humans and their livestock. Infection of the host involves invasion through the intestinal …

High prevalence, potential economic impact, and risk factors of Fasciola hepatica in dairy herds in tropical, dry and temperate climate regions in Mexico

A Villa-Mancera, A Reynoso-Palomar - Acta tropica, 2019 - Elsevier
The aims of this study were to determine the prevalence of fasciolosis in cattle herds and its
influence on production in order to identify potential risk factors in different climate regions …