miRNAs in lung cancer. A systematic review identifies predictive and prognostic miRNA candidates for precision medicine in lung cancer

S Zhong, H Golpon, P Zardo, J Borlak - Translational Research, 2021 - Elsevier
Lung cancer (LC) is the leading cause of cancer-related death worldwide and miRNAs play
a key role in LC development. To better diagnose LC and to predict drug treatment …

Challenges and opportunities of cfDNA analysis implementation in clinical practice: Perspective of the International Society of Liquid Biopsy (ISLB)

C Rolfo, AF Cardona, M Cristofanilli, L Paz-Ares… - Critical Reviews in …, 2020 - Elsevier
Precision medicine was born with the development of new diagnostic techniques and
targeted drugs, yielding better outcomes in cancer care. With the evolution and increasing …

Evaluating the use of circulating microRNA profiles for lung cancer detection in symptomatic patients

T Fehlmann, M Kahraman, N Ludwig, C Backes… - JAMA …, 2020 - jamanetwork.com
Importance The overall low survival rate of patients with lung cancer calls for improved
detection tools to enable better treatment options and improved patient outcomes …

Development of a serum miRNA panel for detection of early stage non-small cell lung cancer

L Ying, L Du, R Zou, L Shi, N Zhang… - Proceedings of the …, 2020 - National Acad Sciences
Minimally invasive testing for early detection of lung cancer to improve patient survival is a
major unmet clinical need. This study aimed to develop and validate a serum multi …

When tissue is an issue the liquid biopsy is nonissue: a review

J Rodríguez, J Avila, C Rolfo, A Ruíz-Patiño… - Oncology and …, 2021 - Springer
Precision medicine has impacted the field of medical oncology by introducing personalized
therapies, improving all measurable outcomes. This field, in turn, has expanded to obtaining …

Contributions of circulating microRNAs for early detection of lung cancer

J Vykoukal, JF Fahrmann, N Patel, M Shimizu… - Cancers, 2022 - mdpi.com
Simple Summary Blood-based cancer biomarkers are a minimally invasive means to
achieve improved assessment of risk and/or earlier detection of lung cancer. Using serum …

MicroRNA‑126: A new and promising player in lung cancer

Q Chen, S Chen, J Zhao, Y Zhou… - Oncology …, 2021 - spandidos-publications.com
Lung cancer is one of the most common malignant tumors associated with cancer death;
however, the mechanisms involved in lung tumor development have not been completely …

Update on liquid biopsy in clinical management of non-small cell lung cancer

Z Wu, Z Yang, Y Dai, Q Zhu, LA Chen - OncoTargets and therapy, 2019 - Taylor & Francis
Lung cancer, a leading cause of cancer-related mortality, has a low rate of early diagnosis
and a poor prognosis for advanced stages. Recent advances in further mastery of the …

Extracellular circulating miRNAs as potential non-invasive biomarkers in non-small cell lung cancer patients

J Raczkowska, A Bielska, A Krętowski… - Frontiers in …, 2023 - frontiersin.org
Non-small cell lung cancer (NSCLC) comprises 85% of all lung cancers and is a malignant
condition resistant to advanced-stage treatment. Despite the advancement in detection and …

MicroRNA‐based biomarkers for diagnosis of non‐small cell lung cancer (NSCLC)

J Liao, J Shen, Q Leng, M Qin, M Zhan… - Thoracic …, 2020 - Wiley Online Library
Background The development of biomarkers for the early detection of non‐small cell lung
cancer (NSCLC) is clinically important. We have developed miRNA biomarkers in sputum …