[HTML][HTML] Palmitic acid: physiological role, metabolism and nutritional implications
Palmitic acid (PA) has been for long time negatively depicted for its putative detrimental
health effects, shadowing its multiple crucial physiological activities. PA is the most common …
health effects, shadowing its multiple crucial physiological activities. PA is the most common …
[HTML][HTML] Bioactive lipids and chronic inflammation: managing the fire within
V Chiurchiù, A Leuti, M Maccarrone - Frontiers in immunology, 2018 - frontiersin.org
Inflammation is an immune response that works as a contained fire that is pre-emptively
sparked as a defensive process during infections or upon any kind of tissue insult, and that …
sparked as a defensive process during infections or upon any kind of tissue insult, and that …
Bioactive lipids, inflammation and chronic diseases
A Leuti, D Fazio, M Fava, A Piccoli, S Oddi… - Advanced Drug Delivery …, 2020 - Elsevier
Endogenous bioactive lipids are part of a complex network that modulates a plethora of
cellular and molecular processes involved in health and disease, of which inflammation …
cellular and molecular processes involved in health and disease, of which inflammation …
Endocannabinoids and endocannabinoid-related mediators: Targets, metabolism and role in neurological disorders
FA Iannotti, V Di Marzo, S Petrosino - Progress in lipid research, 2016 - Elsevier
The endocannabinoid system (ECS) is composed of two G protein-coupled receptors
(GPCRs), the cannabinoid CB1 and CB2 receptors, and the two main endogenous lipid …
(GPCRs), the cannabinoid CB1 and CB2 receptors, and the two main endogenous lipid …
The pharmacology of palmitoylethanolamide and first data on the therapeutic efficacy of some of its new formulations
S Petrosino, V Di Marzo - British journal of pharmacology, 2017 - Wiley Online Library
Palmitoylethanolamide (PEA) has emerged as a potential nutraceutical, because this
compound is naturally produced in many plant and animal food sources, as well as in cells …
compound is naturally produced in many plant and animal food sources, as well as in cells …
[HTML][HTML] Chronic pain in the elderly: mechanisms and distinctive features
A Tinnirello, S Mazzoleni, C Santi - Biomolecules, 2021 - mdpi.com
Background: Chronic pain is a major issue affecting more than 50% of the older population
and up to 80% of nursing homes residents. Research on pain in the elderly focuses mainly …
and up to 80% of nursing homes residents. Research on pain in the elderly focuses mainly …
[HTML][HTML] Palmitoylethanolamide: a natural compound for health management
P Clayton, M Hill, N Bogoda, S Subah… - International journal of …, 2021 - mdpi.com
All nations which have undergone a nutrition transition have experienced increased
frequency and falling latency of chronic degenerative diseases, which are largely driven by …
frequency and falling latency of chronic degenerative diseases, which are largely driven by …
Potential therapeutic targets for intracerebral hemorrhage-associated inflammation: an update
Intracerebral hemorrhage (ICH) is a subtype of stroke with high mortality and disability but
no specific or effective treatment. In the last two decades, much has been learned about the …
no specific or effective treatment. In the last two decades, much has been learned about the …
[HTML][HTML] Mast cells, neuroinflammation and pain in fibromyalgia syndrome
Fibromyalgia Syndrome (FMS) is a disorder of chronic, generalized muscular pain,
accompanied by sleep disturbances, fatigue and cognitive dysfunction. There is no definitive …
accompanied by sleep disturbances, fatigue and cognitive dysfunction. There is no definitive …
[HTML][HTML] Fatty acids: an insight into the pathogenesis of neurodegenerative diseases and therapeutic potential
DJ Vesga-Jiménez, C Martin, GE Barreto… - International journal of …, 2022 - mdpi.com
One of the most common lipids in the human body is palmitic acid (PA), a saturated fatty acid
with essential functions in brain cells. PA is used by cells as an energy source, besides …
with essential functions in brain cells. PA is used by cells as an energy source, besides …