Data from animal models suggest a role of early-life gut microbiota in lung immune
development, and in establishing susceptibility to respiratory infections and asthma in …

Wheezing disorders in children younger than 5 years are common, but lack of clarity
remains about which children should be treated to prevent symptoms and acute episodes …

In microbiome fields of study, meta-analyses have proven to be a valuable tool for identifying
the technical drivers of variation among studies and results of investigations in several …

Background Wheeze is one of the most common symptoms of preschool children (age 1-5
years), yet we have little understanding of the burden in the United Kingdom. Objectives We …

Inspired by the well-known phenomenon of stretch-induced airway dilation in normal lungs
and the emerging stretch-responsive Piezo1 channels that can be chemically activated by …

Viral bronchiolitis, which is most commonly caused by an infection with the respiratory
syncytial virus (RSV), can lead to respiratory difficulties in young children which may require …

Recurrent wheezing (RW) in infancy is one of the most frequent reasons for parents to
consult health care providers and creates a significant global burden. Clinical course of RW …

We describe the prevalence and risk factors for protracted bacterial bronchitis (PBB)
following healthcare presentation for an acute cough illness in children. Data from three …

Introduction Complementing recognition of biomedical phenotypes, a primary care approach
to asthma care recognizes diversity of disease, health beliefs, and lifestyle at a population …

The defining feature of asthma is loss of normal post-natal homeostatic control of airways
smooth muscle (ASM). This is the key feature that distinguishes asthma from all other forms …