[HTML][HTML] Animal models of nonalcoholic fatty liver disease—a starter's guide
MA Van Herck, L Vonghia, SM Francque - Nutrients, 2017 - mdpi.com
Nonalcoholic fatty liver disease (NAFLD) constitutes a major health concern with the
increasing incidence of obesity and diabetes in many Western countries, reaching a …
increasing incidence of obesity and diabetes in many Western countries, reaching a …
De novo lipogenesis in the liver in health and disease: more than just a shunting yard for glucose
FWB Sanders, JL Griffin - Biological Reviews, 2016 - Wiley Online Library
Hepatic de novo lipogenesis (DNL) is the biochemical process of synthesising fatty acids
from acetyl‐CoA subunits that are produced from a number of different pathways within the …
from acetyl‐CoA subunits that are produced from a number of different pathways within the …
[HTML][HTML] Dysregulated m6A modification promotes lipogenesis and development of non-alcoholic fatty liver disease and hepatocellular carcinoma
Y Yang, J Cai, X Yang, K Wang, K Sun, Z Yang… - Molecular Therapy, 2022 - cell.com
Type 2 diabetes mellitus (DM2) is associated closely with non-alcoholic fatty liver disease
(NAFLD) by affecting lipid metabolism, which may lead to non-alcoholic steatohepatitis …
(NAFLD) by affecting lipid metabolism, which may lead to non-alcoholic steatohepatitis …
Plasma proteome profiling discovers novel proteins associated with non‐alcoholic fatty liver disease
Non‐alcoholic fatty liver disease (NAFLD) affects 25% of the population and can progress to
cirrhosis with limited treatment options. As the liver secretes most of the blood plasma …
cirrhosis with limited treatment options. As the liver secretes most of the blood plasma …
[HTML][HTML] Type 2 diabetes mellitus and osteoarthritis
N Veronese, C Cooper, JY Reginster… - Seminars in arthritis and …, 2019 - Elsevier
Objectives Type 2 diabetes mellitus (T2DM) and osteoarthritis (OA) are common diseases
that frequently co-exist, along with overweight/obesity. While the mechanical impact of …
that frequently co-exist, along with overweight/obesity. While the mechanical impact of …
Effects of dietary fructose restriction on liver fat, de novo lipogenesis, and insulin kinetics in children with obesity
Background & Aims Consumption of sugar is associated with obesity, type 2 diabetes
mellitus, nonalcoholic fatty liver disease, and cardiovascular disease. The conversion of …
mellitus, nonalcoholic fatty liver disease, and cardiovascular disease. The conversion of …
Mitochondria, oxidative stress and nonalcoholic fatty liver disease: A complex relationship
A Karkucinska‐Wieckowska… - European journal of …, 2022 - Wiley Online Library
According to the 'multiple‐hit'hypothesis, several factors can act simultaneously in
nonalcoholic fatty liver disease (NAFLD) progression. Increased nitro‐oxidative (nitroso …
nonalcoholic fatty liver disease (NAFLD) progression. Increased nitro‐oxidative (nitroso …
Hepatic lipidomic remodeling in severe obesity manifests with steatosis and does not evolve with non-alcoholic steatohepatitis
Backgrounds & Aims Obesity often leads to non-alcoholic fatty liver disease (NAFLD), which
can progress from simple steatosis (non-alcoholic fatty liver (NAFL)) to non-alcoholic …
can progress from simple steatosis (non-alcoholic fatty liver (NAFL)) to non-alcoholic …
Insulin resistance as a physiological defense against metabolic stress: implications for the management of subsets of type 2 diabetes
Stratifying the management of type 2 diabetes (T2D) has to take into account marked
variability in patient phenotype due to heterogeneity in its pathophysiology, different stages …
variability in patient phenotype due to heterogeneity in its pathophysiology, different stages …
[HTML][HTML] Pathophysiological mechanisms and clinical evidence of relationship between Nonalcoholic fatty liver disease (NAFLD) and cardiovascular disease
R Galiero, A Caturano, E Vetrano, A Cesaro… - Reviews in …, 2021 - imrpress.com
Evidence suggests a close connection between Nonalcoholic Fatty Liver Disease (NAFLD)
and increased cardiovascular (CV) risk. Several cross-sectional studies report that NAFLD is …
and increased cardiovascular (CV) risk. Several cross-sectional studies report that NAFLD is …