Nonalcoholic fatty liver disease (NAFLD) constitutes a major health concern with the
increasing incidence of obesity and diabetes in many Western countries, reaching a …

Hepatic de novo lipogenesis (DNL) is the biochemical process of synthesising fatty acids
from acetyl‐CoA subunits that are produced from a number of different pathways within the …

Type 2 diabetes mellitus (DM2) is associated closely with non-alcoholic fatty liver disease
(NAFLD) by affecting lipid metabolism, which may lead to non-alcoholic steatohepatitis …

Non‐alcoholic fatty liver disease (NAFLD) affects 25% of the population and can progress to
cirrhosis with limited treatment options. As the liver secretes most of the blood plasma …

Objectives Type 2 diabetes mellitus (T2DM) and osteoarthritis (OA) are common diseases
that frequently co-exist, along with overweight/obesity. While the mechanical impact of …

Background & Aims Consumption of sugar is associated with obesity, type 2 diabetes
mellitus, nonalcoholic fatty liver disease, and cardiovascular disease. The conversion of …

According to the 'multiple‐hit'hypothesis, several factors can act simultaneously in
nonalcoholic fatty liver disease (NAFLD) progression. Increased nitro‐oxidative (nitroso …

Backgrounds & Aims Obesity often leads to non-alcoholic fatty liver disease (NAFLD), which
can progress from simple steatosis (non-alcoholic fatty liver (NAFL)) to non-alcoholic …

Stratifying the management of type 2 diabetes (T2D) has to take into account marked
variability in patient phenotype due to heterogeneity in its pathophysiology, different stages …

Evidence suggests a close connection between Nonalcoholic Fatty Liver Disease (NAFLD)
and increased cardiovascular (CV) risk. Several cross-sectional studies report that NAFLD is …