Natural products have long been an important source for discovery of new drugs to treat
human diseases. Piperlongumine (PL) is an amide alkaloid isolated from Piper longum …

Infections caused by parasitic helminths rank among the most prevalent infections of
humans and animals. Toxocariasis, caused by nematodes of the genus Toxocara, is one of …

Since praziquantel is the only drug available to treat schistosomiasis, a neglected parasitic
disease that affects more than 240 million people worldwide, there is an urgent demand for …

Ethnopharmacological relevance Propolis has been used in folk medicine for thousands of
years and, in the past few decades, it has attracted renewed interest. Although propolis has …

The chemical classes of semicarbazones, thiosemicarbazones, and hydrazones are present
in various compounds, each demonstrating diverse biological activities. Extensive studies …

Piplartine (or Piperlongumine) is a natural alkaloid isolated from Piper longum L., which has
been proposed to exhibit various biological properties such as anti-inflammatory effects; …

Schistosomiasis is a widespread human parasitic disease currently affecting over 200
million people, particularly in poor communities. Chemotherapy for schistosomiasis relies …

Schistosomiasis, a parasitic disease caused by the blood fluke of the genus Schistosoma,
affects over 230 million people, especially in developing countries. Despite the significant …

The intravascular parasitic worm Schistosoma mansoni is a causative agent of
schistosomiasis, a disease of great global public health significance. Praziquantel is the only …

Praziquantel is the only available drug to treat schistosomiasis, and therefore, urgent studies
must be performed to identify new anthelmintic agents. This study reports the anthelmintic …