Inflammation and oxidative and nitrosative stresses are linked to depression pathogenesis.
In this context, lipopolysaccharide (LPS) has been used to induce acute inflammation and …

Long-term recurrent stress is a common cause of neuropsychiatric disorders. Animal models
are widely used to study the pathogenesis of stress-related psychiatric disorders. The …

Background Depression is two-to-three times more frequent among women. The
hypothalamus, a sexually dimorphic area, has been implicated in the pathophysiology of …

Depression is an emotional disorder that causes mental and physical changes, and has
limited pharmacotherapy. Tannic acid (TA) is a polyphenol with previously described …

Objective The interleukin-8 (IL-8) has been reported to play an important role in depression,
which might be modulated by the selective serotonin reuptake inhibitors (SSRIs). Thus, the …

Anxiety disorders are the most prevalent psychiatric disorders being also a comorbid state of
other diseases. We aimed to evaluate the anxiolytic‐like effects of carvedilol (CVD), a drug …

Depression and anxiety disorders have their pathophysiologies linked to inflammation and
oxidative stress. In this context, celecoxib (CLX) and etoricoxib (ETR) inhibit cyclooxygenase …

Illness or injury causes an inflammatory state consisting of activation of immune cells and
increased production of cytokines in the periphery and in the brain, resulting changes in …

Endometriosis is a gynecological condition affecting 10% of women in reproductive age.
High rates of depression and anxiety are observed in these patients. The mechanisms …

This study aimed to evaluate the effects of sertraline associated with gold nanoparticles
(AuNPs) in vitro cell viability and in vivo behavior and inflammatory biomarkers in a mouse …