[HTML][HTML] Burden of Clostridioides difficile infection (CDI) - a systematic review of the epidemiology of primary and recurrent CDI
E Finn, FL Andersson, M Madin-Warburton - BMC infectious diseases, 2021 - Springer
Background Clostridioides difficile is a Gram-positive anaerobic bacterium, which causes
Clostridioides difficile infection (CDI). It has been recognised as a leading cause of …
Clostridioides difficile infection (CDI). It has been recognised as a leading cause of …
[PDF][PDF] Synthetic biology in the clinic: engineering vaccines, diagnostics, and therapeutics
Synthetic biology is a design-driven discipline centered on engineering novel biological
functions through the discovery, characterization, and repurposing of molecular parts …
functions through the discovery, characterization, and repurposing of molecular parts …
[HTML][HTML] Strain-level characterization of broad host range mobile genetic elements transferring antibiotic resistance from the human microbiome
Mobile genetic elements (MGEs) carrying antibiotic resistance genes (ARGs) disseminate
ARGs when they mobilise into new bacterial hosts. The nature of such horizontal gene …
ARGs when they mobilise into new bacterial hosts. The nature of such horizontal gene …
[HTML][HTML] Engineering probiotics to inhibit Clostridioides difficile infection by dynamic regulation of intestinal metabolism
Clostridioides difficile infection (CDI) results in significant morbidity and mortality in
hospitalised patients. The pathogenesis of CDI is intrinsically related to the ability of C …
hospitalised patients. The pathogenesis of CDI is intrinsically related to the ability of C …
Synthetic microbial communities (SynComs) of the human gut: design, assembly, and applications
The human gut harbors native microbial communities, forming a highly complex ecosystem.
Synthetic microbial communities (SynComs) of the human gut are an assembly of …
Synthetic microbial communities (SynComs) of the human gut are an assembly of …
Safety of fecal microbiota, live-jslm (REBYOTA™) in individuals with recurrent Clostridioides difficile infection: data from five prospective clinical trials
C Lee, T Louie, L Bancke… - Therapeutic …, 2023 - journals.sagepub.com
Background: Microbiota-based treatments reduce the incidence of recurrent Clostridioides
difficile infections (rCDIs), but prospectively collected safety data needed to broaden patient …
difficile infections (rCDIs), but prospectively collected safety data needed to broaden patient …
[HTML][HTML] Infections in the elderly critically-ill patients
Infections are leading causes of morbidity and mortality in the advanced aged. Various
factors including immunosenescens, comorbid chronic diseases, and alterations in normal …
factors including immunosenescens, comorbid chronic diseases, and alterations in normal …
Advancing therapeutics for recurrent clostridioides difficile infections: an overview of vowst's FDA approval and implications
Clostridioides difficile infections (CDI) are a leading cause of healthcare-associated
infections with a high relapse rate. Current treatment guidelines recommend fidaxomicin as …
infections with a high relapse rate. Current treatment guidelines recommend fidaxomicin as …
Health care resource utilization and costs of recurrent Clostridioides difficile infection in the elderly: a real-world claims analysis
WW Nelson, TA Scott, M Boules, C Teigland… - Journal of Managed …, 2021 - jmcp.org
BACKGROUND: Clostridioides difficile infection (CDI) affected an estimated 365,000
persons in the United States in 2017. Despite a nationally decreasing trend of CDI cases …
persons in the United States in 2017. Despite a nationally decreasing trend of CDI cases …
[HTML][HTML] Bibliometric analysis of peer-reviewed literature on antimicrobial stewardship from 1990 to 2019
WM Sweileh - Globalization and Health, 2021 - Springer
Abstract Background The World Health Organization recommended the implementation of
antimicrobial stewardship (AMS) in the clinical settings to minimize the development and …
antimicrobial stewardship (AMS) in the clinical settings to minimize the development and …