Clostridioides difficile infection (CDI) is an enteric bacterial disease that is increasing in
incidence worldwide. Symptoms of CDI range from mild diarrhea to severe life-threatening …

Clostridioides difficile infection (CDI) continues to affect hospitalized patients and community
populations worldwide. In contrast to the substantial resources invested in the diagnosis and …

Clostridioides difficile is a gram-positive, spore-forming, obligate anaerobe that infects the
colon. C. difficile is estimated to cause nearly half a million cases in the United States …

Objective The objective of this systematic review is to summarize in vitro, preclinical, and
human data related to omadacycline and Clostridioides difficile infection (CDI). Data …

Background Antibiotics and proton pump inhibitors (PPI) are recognized risk factors for
acquisition and recurrence of Clostridioides difficile infection (CDI), yet combined effects …

Abstract Background Clostridium difficile infections (CDIs) cause significant mortality and
morbidity. Critically ill patients are susceptible to CDIs and tend to have severe CDIs, and …

Background Clostridioides difficile (formerly known as Clostridium difficile) is a bacterium
that can cause potentially life‐threatening diarrheal illness in individuals with an unhealthy …

The major toxins of Clostridioides difficile (TcdA, TcdB, CDT) are chromosomally encoded in
nearly all known strains. Following up on previous findings, we identified 5 examples of a …

Clostridioides difficile (C. difficile) is progressively colonizing humans and animals living
with humans. During this process, hypervirulent strains and mutated toxin A and B of C …

Background Antibiotics are a strong risk factor for Clostridioides difficile infection (CDI), and
CDI incidence is often measured as an important outcome metric for antimicrobial …