[HTML][HTML] Mining and unearthing hidden biosynthetic potential
K Scherlach, C Hertweck - Nature Communications, 2021 - nature.com
Genetically encoded small molecules (secondary metabolites) play eminent roles in
ecological interactions, as pathogenicity factors and as drug leads. Yet, these chemical …
ecological interactions, as pathogenicity factors and as drug leads. Yet, these chemical …
Mining genomes to illuminate the specialized chemistry of life
All organisms produce specialized organic molecules, ranging from small volatile chemicals
to large gene-encoded peptides, that have evolved to provide them with diverse cellular and …
to large gene-encoded peptides, that have evolved to provide them with diverse cellular and …
[HTML][HTML] Discovery of non-squalene triterpenes
All known triterpenes are generated by triterpene synthases (TrTSs) from squalene or
oxidosqualene. This approach is fundamentally different from the biosynthesis of short-chain …
oxidosqualene. This approach is fundamentally different from the biosynthesis of short-chain …
A specialized metabolic network selectively modulates Arabidopsis root microbiota
INTRODUCTION Specialized metabolism is a feature of plant evolution and adaption. Plant-
specialized metabolites have ecological functions, mediating interactions between plants …
specialized metabolites have ecological functions, mediating interactions between plants …
[HTML][HTML] More is better: the diversity of terpene metabolism in plants
F Zhou, E Pichersky - Current opinion in plant biology, 2020 - Elsevier
All plants synthesize a diverse array of terpenoid metabolites. Some are common to all, but
many are synthesized only in specific taxa and presumably evolved as adaptations to …
many are synthesized only in specific taxa and presumably evolved as adaptations to …
[HTML][HTML] Terpene synthases as metabolic gatekeepers in the evolution of plant terpenoid chemical diversity
PS Karunanithi, P Zerbe - Frontiers in plant science, 2019 - frontiersin.org
Terpenoids comprise tens of thousands of small molecule natural products that are widely
distributed across all domains of life. Plants produce by far the largest array of terpenoids …
distributed across all domains of life. Plants produce by far the largest array of terpenoids …
[HTML][HTML] Endophytic fungi: hidden treasure chest of antimicrobial metabolites interrelationship of endophytes and metabolites
P Jha, T Kaur, I Chhabra, A Panja, S Paul… - Frontiers in …, 2023 - frontiersin.org
Endophytic fungi comprise host-associated fungal communities which thrive within the
tissues of host plants and produce a diverse range of secondary metabolites with various …
tissues of host plants and produce a diverse range of secondary metabolites with various …
Exploring the diversity of plant metabolism
Plants produce a huge array of metabolites, far more than those produced by most other
organisms. Unraveling this diversity and its underlying genetic variation has attracted …
organisms. Unraveling this diversity and its underlying genetic variation has attracted …
Advances in biosynthesis, regulation, and metabolic engineering of plant specialized terpenoids
DA Nagegowda, P Gupta - Plant Science, 2020 - Elsevier
Plant specialized terpenoids are natural products that have no obvious role in growth and
development, but play many important functional roles to improve the plant's overall fitness …
development, but play many important functional roles to improve the plant's overall fitness …
The complete functional characterisation of the terpene synthase family in tomato
F Zhou, E Pichersky - New Phytologist, 2020 - Wiley Online Library
Analysis of the updated reference tomato genome found 34 full‐length TPS genes and 18
TPS pseudogenes. Biochemical analysis has now identified the catalytic activities of all …
TPS pseudogenes. Biochemical analysis has now identified the catalytic activities of all …