New reliable biomarkers are needed to improve individual risk assessment for post‐
transplant infection, acute graft rejection and other immune‐related complications after solid …

Balancing immunosuppression to prevent rejection in solid organ transplant (SOT)
recipients remains challenging. Torque teno virus (TTV), a commensal non‐pathogenic …

Importance Fewer than 50% of kidney transplant recipients (KTRs) develop antibodies
against the SARS-CoV-2 spike protein after 2 doses of an mRNA vaccine. Preliminary data …

Background Late antibody-mediated rejection (ABMR) is a leading cause of transplant
failure. Blocking IL-6 has been proposed as a promising therapeutic strategy. Methods We …

Background Urine CXCL10 is a promising noninvasive biomarker for detection of renal
allograft rejection. The aim of this study was to investigate the clinical utility of renal allograft …

Potent immunosuppressive drugs have been introduced into clinical care for solid organ
transplant recipients. It is now time to guide these drugs on an individual level to optimize …

Background Immunosuppressed individuals such as kidney transplant recipients (KTR) and
hemodialysis patients (DP) show impaired immune responses to COVID-19 vaccination …

BK polyomavirus nephropathy (BKVN) and allograft rejection are two closely-associated
diseases on opposite ends of the immune scale in kidney transplant recipients. The principle …

Anelloviridae and Redondoviridae are virus families with small, circular, single-stranded
DNA genomes that are common components of the human virome. Despite their small …

Torquetenovirus (TTV), a small, single stranded anellovirus, is currently being explored as a
marker of immunocompetence in patients with immunological impairment and inflammatory …