Abstract Machine learning methods have been employed to make predictions in psychiatry
from genotypes, with the potential to bring improved prediction of outcomes in psychiatric …

Unraveling the genetic basis of organismal form and function remains one of the major goals
of evolutionary biology. Theory has long supported a model of polygenic evolution in which …

The challenge of precision medicine is to model complex interactions among DNA variants,
phenotypes, development, environments, and treatments. We address this challenge by …

The building envelope considerably influences building energy consumption. To enhance
the energy efficiency of buildings, this paper proposes an approach to predict building …

The analysis of large genomic data is hampered by issues such as a small number of
observations and a large number of predictive variables (commonly known as “large P small …

Background Recurrence and chemoresistance constitute the leading cause of death in
colorectal cancer (CRC). Thus, it is of great significance to clarify the underlying …

Background: Although numerous studies are conducted every year on how to reduce the
fatality rate associated with sepsis, it is still a major challenge faced by patients, clinicians …

Large genomic studies are becoming increasingly common with advances in sequencing
technology, and our ability to understand how genomic variation influences phenotypic …

Background: IsomiR is an isoform of microRNA (miRNA), and its sequences vary from those
of a reference miRNA, which arose with the advencements of deep sequencing, high miRNA …

Technological advancements of the last decades sparked an explosion in the amounts of
data acquired in several scientific fields. In particular, high-throughput technologies have …