[HTML][HTML] Microbiota in health and diseases

K Hou, ZX Wu, XY Chen, JQ Wang, D Zhang… - Signal transduction and …, 2022 - nature.com
The role of microbiota in health and diseases is being highlighted by numerous studies
since its discovery. Depending on the localized regions, microbiota can be classified into …

Interleukin-17 and innate immunity in infections and chronic inflammation

N Isailovic, K Daigo, A Mantovani, C Selmi - Journal of autoimmunity, 2015 - Elsevier
Abstract Interleukin 17 (IL-17) includes several cytokines among which IL-17A is considered
as one of the major pro-inflammatory cytokine being central to the innate and adaptive …

Th1 and Th17 cells in tuberculosis: protection, pathology, and biomarkers

IV Lyadova, AV Panteleev - Mediators of inflammation, 2015 - Wiley Online Library
The outcome of Mycobacterium tuberculosis (Mtb) infection ranges from a complete
pathogen clearance through asymptomatic latent infection (LTBI) to active tuberculosis (TB) …

Role of IL-17 in asthma pathogenesis and its implications for the clinic

RK Ramakrishnan, S Al Heialy… - Expert review of …, 2019 - Taylor & Francis
Introduction: Asthma is a respiratory disorder typically characterized by T-helper type 2 (Th2)
inflammation that is mediated by cytokines, including IL-4, IL-5, and IL-13 …

Interleukin-17 in human inflammatory diseases

AG Shabgah, E Fattahi, FZ Shahneh - Advances in Dermatology and …, 2014 - termedia.pl
Human Th17 pro-inflammatory cells are currently defined as cells that produce IL-17A and F,
tumor necrosis factor (TNF)-α, IL-6, IL-21, IL-22 and IL-23. Recently discovered related …

Profibrotic effect of IL-17A and elevated IL-17RA in idiopathic pulmonary fibrosis and rheumatoid arthritis-associated lung disease support a direct role for IL-17A/IL …

J Zhang, D Wang, L Wang, S Wang… - … of Physiology-Lung …, 2019 - journals.physiology.org
Interleukin (IL)-17 is a T helper 17 cytokine implicated in the pathogenesis of many
autoimmune diseases, including rheumatoid arthritis (RA). Although IL-17A has a well …

Intestinal microbiota of mice influences resistance to Staphylococcus aureus pneumonia

S Gauguet, S D'Ortona, K Ahnger-Pier… - Infection and …, 2015 - Am Soc Microbiol
Th17 immunity in the gastrointestinal tract is regulated by the intestinal microbiota
composition, particularly the presence of segmented filamentous bacteria (sfb), but the role …

Emerging roles of T helper 17 and regulatory T cells in lung cancer progression and metastasis

EA Marshall, KW Ng, SHY Kung, EM Conway… - Molecular cancer, 2016 - Springer
Lung cancer is a leading cause of cancer-related deaths worldwide. Lung cancer risk
factors, including smoking and exposure to environmental carcinogens, have been linked to …

[HTML][HTML] Role of IL-6 in the commitment of T cell subsets

T Korn, M Hiltensperger - Cytokine, 2021 - Elsevier
IL-6 gained much attention with the discovery that this cytokine is a non-redundant
differentiation factor for Th17 cells and T follicular helper cells. Adaptive immune responses …

A case for targeting Th17 cells and IL-17A in SARS-CoV-2 infections

M Orlov, PL Wander, ED Morrell… - The Journal of …, 2020 - journals.aai.org
Abstract SARS-CoV-2, the virus causing COVID-19, has infected millions and has caused
hundreds of thousands of fatalities. Risk factors for critical illness from SARS-CoV-2 infection …