Nanoparticles in tumor microenvironment remodeling and cancer immunotherapy

Q Lu, D Kou, S Lou, M Ashrafizadeh, AR Aref… - Journal of Hematology & …, 2024 - Springer
Cancer immunotherapy and vaccine development have significantly improved the fight
against cancers. Despite these advancements, challenges remain, particularly in the clinical …

Unraveling the enigma of tumor-associated macrophages: challenges, innovations, and the path to therapeutic breakthroughs

S Shao, H Miao, W Ma - Frontiers in Immunology, 2023 - frontiersin.org
Tumor-associated macrophages (TAMs) are integral to the tumor microenvironment (TME),
influencing cancer progression significantly. Attracted by cancer cell signals, TAMs exhibit …

Unveiling the immune microenvironment's role in breast cancer: A glimpse into promising frontiers

A Kotsifaki, N Alevizopoulos, V Dimopoulou… - International Journal of …, 2023 - mdpi.com
Breast cancer (BC), one of the most widespread and devastating diseases affecting women
worldwide, presents a significant public health challenge. This review explores the emerging …

Cytokines and soluble mediators as architects of tumor microenvironment reprogramming in cancer therapy

S Xu, Q Wang, W Ma - Cytokine & Growth Factor Reviews, 2024 - Elsevier
Navigating the intricate landscape of the tumor microenvironment (TME) unveils a pivotal
arena for cancer therapeutics, where cytokines and soluble mediators emerge as double …

Truncated O-glycosylation in metastatic triple-negative breast cancer reveals a gene expression signature associated with extracellular matrix and proteolysis

MF Festari, E Jara, M Costa, A Iriarte, T Freire - Scientific Reports, 2024 - nature.com
Breast cancer (BC) is the leading cause of death by cancer in women worldwide. Triple-
negative (TN) BC constitutes aggressive and highly metastatic tumors associated with …

Baseline interleukin-6 is a prognostic factor for patients with metastatic breast cancer treated with eribulin

A Bun, M Nagahashi, M Kuroiwa, M Komatsu… - Breast Cancer Research …, 2023 - Springer
Purpose Eribulin is a unique anti-cancer drug which can improve overall survival (OS) of
patients with metastatic breast cancer (MBC), probably by modulating the tumor immune …

A potential cure for tumor‐associated immunosuppression by Toxoplasma gondii

N Lotfalizadeh, S Sadr, S Morovati… - Cancer …, 2024 - Wiley Online Library
Background Recently, immunotherapy has become very hopeful for cancer therapy. Cancer
treatment through immunotherapy has excellent specificity and less toxicity than …

Transcriptomics and metabonomics study on the effect of exercise combined with curcumin supplementation on breast cancer in mice

Y Guo, J Su, S Jiang, Y Xu, B Dou, T Li, J Zhu, K He - Heliyon, 2024 - cell.com
Curcumin and exercise have been reported to show good anti-tumour effects. However,
relevant research on the combined effects of physical exercise and curcumin …

Preoperative systemic immune-inflammation index is a potential biomarker in adult patients with high-grade gliomas undergoing radical resection

YT Jiang, TC Wang, W Zhang - Journal of Inflammation Research, 2023 - Taylor & Francis
Background Increasing evidence has highlighted that systemic immune-inflammation index
(SII), a recently developed prognostic biomarker that utilizes peripheral platelet, lymphocyte …

Currently Used Methods to Evaluate the Efficacy of Therapeutic Drugs and Kidney Safety

HJ Huang, CL Chou, TT Sandar, WC Liu, HC Yang… - Biomolecules, 2023 - mdpi.com
Kidney diseases with kidney failure or damage, such as chronic kidney disease (CKD) and
acute kidney injury (AKI), are common clinical problems worldwide and have rapidly …