Mammalian eggs (oocytes) are formed during fetal life and establish associations with
somatic cells to form primordial follicles that create a store of germ cells (the primordial pool) …

The mitochondria, present in almost all eukaryotic cells, produce energy but also contribute
to many other essential cellular functions. One of the unique characteristics of the …

In mammalian ovaries, oocytes are physically coupled to somatic granulosa cells, and this
coupling is crucial for the growth and development of competent oocytes as it mediates the …

Mitochondrial function and glucose metabolism play important roles in bidirectional
signaling between granulosa cells (GCs) and oocytes. However, the factors associated with …

Progressive loss of physiological integrity and accumulation of degenerative changes
leading to functional impairment and increased susceptibility to diseases are the main …

Early embryonic arrest and fragmentation (EEAF) is a common phenomenon leading to
female infertility, but the genetic determinants remain largely unknown. The Moloney …

Chemo‐phototherapy has emerged as a promising approach to complement traditional
cancer treatment and enhance therapeutic effects. However, it still faces the challenges of …

BACKGROUND Fertility loss during female ageing is associated with increasing basal FSH
and decreasing anti-Müllerian hormone (AMH) concentrations, together with compromised …

BACKGROUND While oocyte IVM is practiced sporadically it has not achieved widespread
clinical practice globally. However, recently there have been some seminal advances in our …

Oocyte developmental potential is intimately linked to metabolism. Existing approaches to
measure metabolism in the cumulus oocyte complex (COC) do not provide information on …