Mito-Q promotes porcine oocytes maturation by maintaining mitochondrial thermogenesis via UCP2 downregulation

D Zhou, Q Zhuan, Y Luo, H Liu, L Meng, X Du, G Wu… - Theriogenology, 2022 - Elsevier
Mitochondrial thermogenesis is an adaptive response of cells to their surrounding stress.
Oxidative stress is one of the common stresses during in vitro maturation (IVM) of oocytes …

Oocyte-cumulus cells crosstalk: New comparative insights

C Martinez Serrano, D Rizos, H Rodriguez-Martinez… - …, 2023 - diva-portal.org
Mammalian follicles are constituted of a complex structure composed of several layers of
granulosa cells surrounding the oocyte and of theca cells that reside beneath its basement …

[HTML][HTML] Intercellular communication in the cumulus–oocyte complex during folliculogenesis: A review

J Xie, X Xu, S Liu - Frontiers in Cell and Developmental Biology, 2023 - frontiersin.org
During folliculogenesis, the oocyte and surrounding cumulus cells form an ensemble called
the cumulus-oocyte complex (COC). Due to their interdependence, research on the COC …

[HTML][HTML] Oocyte metabolic function, lipid composition, and developmental potential are altered by diet in older mares

GD Catandi, L LiPuma, YM Obeidat… - …, 2022 - rep.bioscientifica.com
Dietary supplementation is the most feasible method to improve oocyte function and
developmental potential in vivo. During three experiments, oocytes were collected from …

[HTML][HTML] SIRT2 is critical for sheep oocyte maturation through regulating function of surrounding granulosa cells

X Fang, W Xia, S Li, Y Qi, M Liu, Y Yu, H Li, M Li… - International Journal of …, 2022 - mdpi.com
Oocyte in vitro maturation is crucial for in vitro embryo production technology, which
provides oocytes resources for in vitro fertilization and somatic cell nuclear transfer. Previous …

[HTML][HTML] Bitter taste receptors expression in human granulosa and cumulus cells: New perspectives in female fertility

B Semplici, FP Luongo, S Passaponti, C Landi… - Cells, 2021 - mdpi.com
Bitter taste receptors (TAS2RS) expression is not restricted to the oral cavity and the
presence of these receptors in the male reproductive system and sperm provides insights …

Obese outbred mice only partially benefit from diet normalization or calorie restriction as preconception care interventions to improve metabolic health and oocyte …

A Smits, WFA Marei, K Moorkens, PEJ Bols… - Human …, 2022 - academic.oup.com
STUDY QUESTION Can diet normalization or a calorie-restricted diet for 2 or 4 weeks be
used as a preconception care intervention (PCCI) in Western-type diet-induced obese Swiss …

[HTML][HTML] Non-invasive assessment of oocyte developmental competence

TCY Tan, KR Dunning - Reproduction, Fertility and Development, 2022 - CSIRO Publishing
Oocyte quality is a key factor influencing IVF success. The oocyte and surrounding cumulus
cells, known collectively as the cumulus oocyte complex (COC), communicate bi …

[HTML][HTML] Diet normalization or caloric restriction as a preconception care strategy to improve metabolic health and oocyte quality in obese outbred mice

A Smits, WFA Marei, D De Neubourg… - Reproductive Biology …, 2021 - Springer
Background Maternal metabolic disorders are linked to reduced metabolic health and
oocyte quality. Obese women are advised to lose weight before conception to increase …

Neuregulin 1 (NRG1) modulates oocyte nuclear maturation during IVM and improves post-IVF embryo development

TT Dellaqua, RA Vígaro, LCZ Janini, M Dal Canto… - Theriogenology, 2023 - Elsevier
Oocyte in vitro maturation (IVM) is still a major challenge in human and animal assisted
reproduction. Gradual instead of abrupt activation of the ovulatory cascade during IVM has …