International Union of Basic and Clinical Pharmacology. CV. Somatostatin receptors: structure, function, ligands, and new nomenclature
T Günther, G Tulipano, P Dournaud, C Bousquet… - Pharmacological …, 2018 - ASPET
Somatostatin, also known as somatotropin-release inhibitory factor, is a cyclopeptide that
exerts potent inhibitory actions on hormone secretion and neuronal excitability. Its …
exerts potent inhibitory actions on hormone secretion and neuronal excitability. Its …
Epigenetic regulation of somatostatin and somatostatin receptors in neuroendocrine tumors and other types of cancer
MJ Klomp, SU Dalm, M De Jong, RA Feelders… - Reviews in Endocrine …, 2021 - Springer
Both somatostatin (SST) and somatostatin receptors (SSTRs) are proteins with important
functions in both physiological tissue and in tumors, particularly in neuroendocrine tumors …
functions in both physiological tissue and in tumors, particularly in neuroendocrine tumors …
Increased 68Ga-DOTATATE uptake in PET imaging discriminates meningioma and tumor-free tissue
W Rachinger, VM Stoecklein, NA Terpolilli… - Journal of Nuclear …, 2015 - Soc Nuclear Med
Meningiomas are known to express somatostatin receptor 2 (SSTR2). PET using the SSTR2
analog 68Ga-DOTATATE has recently been introduced for imaging of meningiomas …
analog 68Ga-DOTATATE has recently been introduced for imaging of meningiomas …
CX3CR1 acts as a protective biomarker in the tumor microenvironment of colorectal cancer
Y Yue, Q Zhang, Z Sun - Frontiers in immunology, 2022 - frontiersin.org
The tumor microenvironment (TME) plays an important role in the pathogenesis of many
cancers. We aimed to screen the TME-related hub genes of colorectal adenoma (CRAD) …
cancers. We aimed to screen the TME-related hub genes of colorectal adenoma (CRAD) …
Photocatalytic degradation of malachite green dye by ZnO and ZnO–β-cyclodextrin nanocomposite
Water, the primary source of life, is contaminated with various organic/inorganic impurities in
the course of development. Organic dyes, a waste product from dying industries, have …
the course of development. Organic dyes, a waste product from dying industries, have …
Somatostatin and Somatostatin Receptors in Tumour Biology
U Kumar - International Journal of Molecular Sciences, 2023 - mdpi.com
Somatostatin (SST), a growth hormone inhibitory peptide, is expressed in endocrine and
non-endocrine tissues, immune cells and the central nervous system (CNS). Post-release …
non-endocrine tissues, immune cells and the central nervous system (CNS). Post-release …
Peptide receptor targeting in cancer: the somatostatin paradigm
F Barbieri, A Bajetto, A Pattarozzi… - … journal of peptides, 2013 - Wiley Online Library
Peptide receptors involved in pathophysiological processes represent promising therapeutic
targets. Neuropeptide somatostatin (SST) is produced by specialized cells in a large number …
targets. Neuropeptide somatostatin (SST) is produced by specialized cells in a large number …
Colon cancer transcriptome
K Mokhtari, M Peymani, M Rashidi… - Progress in biophysics …, 2023 - Elsevier
Over the last four decades, methodological innovations have continuously changed
transcriptome profiling. It is now feasible to sequence and quantify the transcriptional outputs …
transcriptome profiling. It is now feasible to sequence and quantify the transcriptional outputs …
Cetuximab conjugated with octreotide and entrapped calcium alginate-beads for targeting somatostatin receptors
There is a need to formulate oral cetuximab (CTX) for targeting colorectal cancer, which is
reported to express somatostatin receptors (SSTRs). Therefore, coating CTX with a …
reported to express somatostatin receptors (SSTRs). Therefore, coating CTX with a …
Somatostatin receptor 2 signaling promotes growth and tumor survival in small‐cell lung cancer
JM Lehman, MD Hoeksema, J Staub… - … journal of cancer, 2019 - Wiley Online Library
Somatostatin receptor 2 (SSTR2) is overexpressed in a majority of neuroendocrine
neoplasms, including small‐cell lung carcinomas (SCLCs). SSTR2 was previously …
neoplasms, including small‐cell lung carcinomas (SCLCs). SSTR2 was previously …