Role of platelets in the pathogenesis of delayed injury after subarachnoid hemorrhage

A Dienel, P Kumar T, SL Blackburn… - Journal of Cerebral …, 2021 - journals.sagepub.com
Aneurysmal subarachnoid hemorrhage (aSAH) patients develop delayed cerebral ischemia
and delayed deficits (DCI) within 2 weeks of aneurysm rupture at a rate of approximately …

The blood–brain barrier and the neurovascular unit in subarachnoid hemorrhage: molecular events and potential treatments

P Solár, A Zamani, K Lakatosová, M Joukal - Fluids and Barriers of the …, 2022 - Springer
The response of the blood–brain barrier (BBB) following a stroke, including subarachnoid
hemorrhage (SAH), has been studied extensively. The main components of this reaction are …

Cerebral vasospasm: current understanding

GSU Rao, R Muthuchellappan - Current Opinion in …, 2016 - journals.lww.com
Cerebral vasospasm: current understanding : Current Opinion in Anesthesiology Cerebral
vasospasm: current understanding : Current Opinion in Anesthesiology Log in or Register …

Progressive shrinkage of involved arteries in parallel with disease progression in moyamoya disease

S Yamamoto, D Kashiwazaki, N Akioka… - World Neurosurgery, 2019 - Elsevier
Objective Recent three-dimensional constructive interference in steady state (3D-CISS)
studies have shown that the involved arteries decrease not only their own luminal caliber but …

Current understanding of the molecular mechanism between hemodynamic-induced intracranial aneurysm and inflammation

H Tang, Y Luo, Q Zuo, C Wang… - Current Protein and …, 2019 - ingentaconnect.com
Intracranial aneurysms (IA) are a huge threat to human health, with a global incidence rate
of 0.65–8.4%. Although the microsurgical and interventional techniques have made …

Therapeutically targeting platelet-derived growth factor-mediated signaling underlying the pathogenesis of subarachnoid hemorrhage-related vasospasm

MGZ Ghali, VM Srinivasan, J Johnson, P Kan… - Journal of Stroke and …, 2018 - Elsevier
Introduction Vasospasm accounts for a large fraction of the morbidity and mortality burden in
patients sustaining subarachnoid hemorrhage (SAH). Platelet-derived growth factor (PDGF) …

Imatinib attenuates cerebrovascular injury and phenotypic transformation after intracerebral hemorrhage in rats

WJ Pearce, C Doan, D Carreon… - American Journal …, 2016 - journals.physiology.org
This study explored the hypothesis that intracerebral hemorrhage (ICH) promotes release of
diffusible factors that can significantly influence the structure and function of cerebral arteries …

Poor expression of miR‐195‐5p can assist the diagnosis of cerebral vasospasm after subarachnoid hemorrhage and predict adverse outcomes

Y Li, S Yang, X Zhou, R Lai - Brain and Behavior, 2022 - Wiley Online Library
Objective Patients with spontaneous subarachnoid hemorrhage (SAH) may develop
refractory arterial cerebral vasospasm (CVS), which is the leading cause of death in SAH …

The rise of soluble platelet-derived growth factor receptor β in CSF early after subarachnoid hemorrhage correlates with cerebral vasospasm

J Liu, Z Ye, S Lv, Z Zhuang, X Zhang, X Zhang… - Neurological …, 2018 - Springer
Platelet-derived growth factor β (PDGFβ) has been proposed to contribute to the
development of cerebral vasospasm (CVS) after subarachnoid hemorrhage (SAH), and …

Ethyl pyruvate attenuates early brain injury following subarachnoid hemorrhage in the endovascular perforation rabbit model possibly via anti-inflammation and …

T Lv, YF Miao, YC Jin, SF Yang, H Wu, J Dai… - Neurochemical …, 2017 - Springer
Early brain injury (EBI) following subarachnoid hemorrhage (SAH) is the main cause to poor
outcomes of SAH patients, and early inflammation plays an important role in the acute …