The Nerve Growth Factor Receptor (NGFR/p75NTR): A Major Player in Alzheimer's Disease

F Bruno, P Abondio, A Montesanto, D Luiselli… - International journal of …, 2023 - mdpi.com
Alzheimer's disease (AD) represents the most prevalent type of dementia in elderly people,
primarily characterized by brain accumulation of beta-amyloid (Aβ) peptides, derived from …

Rare amyloid precursor protein point mutations recapitulate worldwide migration and admixture in healthy individuals: Implications for the study of neurodegeneration

P Abondio, F Bruno, AC Bruni, D Luiselli - International Journal of …, 2022 - mdpi.com
Genetic discoveries related to Alzheimer's disease and other dementias have been
performed using either large cohorts of affected subjects or multiple individuals from the …

The role of neurotransmitter receptors in antipsychotic medication efficacy for Alzheimer's-related psychosis

B Sharma, S Das, A Mazumder, DS Rautela… - The Egyptian Journal of …, 2024 - Springer
Background Alzheimer's disease (AD) is marked by cognitive decline along with the
presence of mental symptoms, most notably psychosis. Although antipsychotic drugs are …

Thymic function and survival at advance ages in nursing home residents from Southern Italy

E Paparazzo, S Geracitano, V Lagani, L Citrigno… - Immunity & …, 2023 - Springer
Background Immunosenescence is a complex process characterized by an age-related
remodelling of immune system. The prominent effects of the immunosenescence process is …

Mutational Landscape of Alzheimer's Disease and Frontotemporal Dementia: Regional Variances in Northern, Central, and Southern Italy

C Saraceno, L Pagano, V Laganà, A Geviti… - International Journal of …, 2024 - mdpi.com
Alzheimer's Disease (AD) and Frontotemporal Dementia (FTD) are the two major
neurodegenerative diseases with distinct clinical and neuropathological profiles. The aim of …

Occupation, Literacy, Anthropometric Traits, and Life Expectancy of Italian Men Born 1900–1910: Evidence From Military Conscription Registers

F Bruno, MA Aceto, P Abondio… - Journal of Aging …, 2023 - journals.sagepub.com
Objective The aim is to explore the role of anthropometric traits and sociodemographic
characteristics on human survival. Methods Anthropometrics and sociodemographic data of …

Genetic variability of FOXP2 and its targets CNTNAP2 and PRNP in frontotemporal dementia: A pilot study in a southern Italian population

P Crocco, F De Rango, F Bruno, A Malvaso, R Maletta… - Heliyon, 2024 - cell.com
Abstract The Forkhead box P2 (FOXP2) is an evolutionary conserved transcription factor
involved in the maintenance of neuronal networks, implicated in language disorders. Some …

Using the Theory of Planned Behavior and Past Behavior to Explain the Intention to Receive a Seasonal Influenza Vaccine among Family Caregivers of People with …

F Bruno, P Abondio, V Laganà, R Colao… - International Journal of …, 2023 - mdpi.com
Older adults with dementia present an increased risk of mortality due to seasonal influenza.
Despite concerning evidence, the influenza vaccination program has been unsuccessful …