Abstract High lipoprotein (a)[Lp (a)] concentrations are one of the most important genetically
determined risk factors for cardiovascular disease. Lp (a) concentrations are an enigmatic …

Lipoprotein (a)[Lp (a)] has attracted the interest of researchers and physicians due to its
intriguing properties, including an intragenic multiallelic copy number variation in the LPA …

Mendelian randomization (MR) studies typically assess the pathogenic relevance of
environmental exposures or disease biomarkers, using genetic variants that instrument …

Plasma lipoprotein (a)[L p (a)] is a quantitative genetic trait with a very broad and skewed
distribution, which is largely controlled by genetic variants at the LPA locus on chromosome …

Background An increased level of Lp (a) lipoprotein has been identified as a risk factor for
coronary artery disease that is highly heritable. The genetic determinants of the Lp (a) …

The bacterial composition of the human fecal microbiome is influenced by many lifestyle
factors, notably diet. It is less clear, however, what role host genetics plays in dictating the …

Human epidemiologic and genetic evidence using the Mendelian randomization approach
in large-scale studies now strongly supports that elevated lipoprotein (a)[Lp (a)] is a causal …

Levels of lipoprotein (a)[Lp (a)], a complex between an LDL-like lipid moiety containing one
copy of apoB, and apo (a), a plasminogen-derived carbohydrate-rich hydrophilic protein, are …

Abstract Lipoprotein (a)[Lp (a)] is a highly atherogenic lipoprotein that is under strong
genetic control by the LPA gene locus. Genetic variants including a highly polymorphic copy …

High lipoprotein (a)[Lp (a)] concentrations are an independent risk factor for cardiovascular
outcomes. Concentrations are strongly influenced by apo (a) kringle IV repeat isoforms. We …