The nucleotide-binding domain leucine-rich repeat and pyrin domain containing receptor
protein 3 (NLRP3) is an important pattern recognition receptor in human innate immunity …

Alzheimer's disease (AD) is one of the most prevalent neurodegenerative disorders. The
etiology and pathology of AD are complicated, variable, and yet to be completely …

Pyroptosis is a newly discovered form of cell death. Peroxiredoxin 3 (PRX3) plays a crucial
role in scavenging reactive oxygen species (ROS), but its hepatoprotective capacity in …

Ferroptosis is a novel iron-dependent cell death pathway mainly caused by an abnormal
redox state and associated with various diseases including cancer. Recently, much attention …

The liver is vulnerable to sepsis, and sepsis‐induced liver injury is closely associated with
poor survival of sepsis patients. Studies have found that the overproduction of reactive …

Objective This study aimed to explore the mechanism of Nobiletin attenuating Alzheimer's
disease (AD) by inhibiting neuroinflammation. Methods The expression of inflammatory …

Increasingly prevalent acute and chronic human brain diseases are scourges for the elderly.
Besides the lack of therapies, these ailments share a neuroinflammation that is …

Abstract Background Postoperative Cognitive Dysfunction (POCD) has attracted increased
attention, but its precise mechanism remains to be explored. This study aimed to figure out …

In this study Bacillus amyloliquefaciens RK3 was isolated from a sugar mill effluent-
contaminated soil and utilised to generate a potential polysaccharide with anti-Alzheimer's …

Alzheimer's disease (AD) is the most common cause of dementia. In recent years, several
studies have robustly shown that neuroinflammation plays a crucial role in the …