Modelling viral and immune system dynamics

AS Perelson - Nature reviews immunology, 2002 - nature.com
During the past 6 years, there have been substantial advances in our understanding of
human immunodeficiency virus 1 and other viruses, such as hepatitis B virus and hepatitis C …

[HTML][HTML] The spread, treatment, and prevention of HIV-1: evolution of a global pandemic

MS Cohen, N Hellmann, JA Levy… - The Journal of …, 2008 - Am Soc Clin Investig
The most up-to-date estimates demonstrate very heterogeneous spread of HIV-1, and more
than 30 million people are now living with HIV-1 infection, most of them in sub-Saharan …

Human immunodeficiency virus (HIV)

GAC Blood - Transfusion Medicine and Hemotherapy, 2016 - karger.com
German Advisory Committee Blood (Arbeitskreis Blut), Subgroup 'Assessment of Pathogens
Transmissible by Blood'tein, TM) are derived. In addition to the structural proteins, the HIV …

The Trojan exosome hypothesis

SJ Gould, AM Booth… - Proceedings of the …, 2003 - National Acad Sciences
We propose that retroviruses exploit a cell-encoded pathway of intercellular vesicle traffic,
exosome exchange, for both the biogenesis of retroviral particles and a low-efficiency but …

HIV pathogenesis: 25 years of progress and persistent challenges

JA Levy - Aids, 2009 - journals.lww.com
In 1981, a new disease syndrome appeared in human populations in the United States and
elsewhere characterized by a deficiency in the immune system [1]. Patients presented with …

Association of depression with viral load, CD8 T lymphocytes, and natural killer cells in women with HIV infection

DL Evans, TR Ten Have, SD Douglas… - American Journal of …, 2002 - Am Psychiatric Assoc
OBJECTIVE: Clinical and epidemiology studies have implicated depression as a risk factor
in the morbidity and mortality of many human diseases. This study sought to determine if …

Depletion of circulating natural type 1 interferon-producing cells in HIV-infected AIDS patients

V Soumelis, I Scott, F Gheyas… - Blood, The Journal …, 2001 - ashpublications.org
Natural interferon-α producing cells (IPCs) are a newly characterized blood cell type, which
is the major source of type I interferons in antiviral innate immune responses. The …

Astrocytes: HIV cellular reservoirs and important participants in neuropathogenesis

R Brack-Werner - Aids, 1999 - journals.lww.com
HIV can invade cells of the central nervous system (CNS) and cause progressive combined
cognitive and motor impairment in infected individuals. The cellular basis and mechanisms …

Human immunodeficiency virus type 1 attachment to HeLa CD4 cells is CD4 independent and gp120 dependent and requires cell surface heparans

I Mondor, S Ugolini, QJ Sattentau - Journal of virology, 1998 - Am Soc Microbiol
The binding of human immunodeficiency virus type 1 (HIV-1)(Hx10) virions to two different
cell lines was analyzed by using a novel assay based on the detection, by anti-HLA-DR …

[HTML][HTML] SARS-CoV-2 RNA elements share human sequence identity and upregulate hyaluronan via NamiRNA-enhancer network

W Li, S Yang, P Xu, D Zhang, Y Tong, L Chen, B Jia… - …, 2022 - thelancet.com
Summary Background Since late 2019, SARS-CoV-2 infection has resulted in COVID-19
accompanied by diverse clinical manifestations. However, the underlying mechanism of how …