G-protein-coupled receptors (GPCRs) are the largest family of cell surface signaling
receptors known to play a crucial role in various physiological functions, including tumor …

Olfactory and taste receptors are expressed primarily in the nasal olfactory epithelium and
gustatory taste bud cells, where they transmit real-time sensory signals to the brain …

T cells are an essential part of the immune system with crucial roles in adaptive response
and the maintenance of tissue homeostasis. Depending on their microenvironment, T cells …

The control over the extent and timing of G protein signaling is provided by the regulator of G
protein signaling (RGS) proteins that deactivate G protein α subunits (Gα). Mammalian …

G protein‐coupled receptors (GPCRs) and heterotrimeric G proteins play central roles in a
diverse array of cellular processes. As such, dysregulation of GPCRs and their coupled …

Uveal melanoma (UM), a rare cancer of the eye, is distinct from cutaneous melanoma by its
etiology, the mutation frequency and profile, and its clinical behavior including resistance to …

Aims This study aims to explore the function and mechanism of G Protein-coupled receptor
class C group 5 member A (GPRC5A) in docetaxel-resistance and liver metastasis of breast …

G protein-coupled receptors (GPCRs) constitute the largest and most diverse protein family
in the human genome with over 800 members identified to date. They play critical roles in …

G protein–coupled receptors (GPCRs) are the largest gene family of cell membrane–
associated molecules mediating signal transmission, and their involvement in key …

Regulation of tissue size requires fine tuning at the single-cell level of proliferation rate, cell
volume, and cell death. Whereas the adjustment of proliferation and growth has been widely …